Results 131 to 140 of about 26,465 (226)

The PRAGMATIC pathway ‐ PRostate cancer diAGnosis and MAnagement Triage In Clinical care

open access: yesBJU International, Volume 137, Issue 5, Page 849-857, May 2026.
Objectives To investigate whether nurse navigator‐led triaging of high‐risk patients may reduce prostate cancer (PCa) diagnosis and treatment times using an in‐house bespoke PRostate cancer diAGnosis and MAnagement Triage In the Clinial care pathway (PRAGMATIC) triaging system, as locally advanced/metastatic disease should be diagnosed and treated ...
Abhishek Sharma   +28 more
wiley   +1 more source

The role of the reference alternative in the specification of asymmetric discrete choice models [PDF]

open access: yes
Within the discrete choice modelling literature, there has been growing interest in including reference alternatives within stated choice survey tasks.
John M. Rose, Lorenzo Masiero
core  

Single‐Cell Analysis Identified a Recurrent Malignant‐Associated Transcriptional State in Colorectal Cancer

open access: yesCancer Science, Volume 117, Issue 5, Page 1397-1411, May 2026.
Colorectal cancer (CRC) shows high molecular heterogeneity, yet single‐cell data from Japanese patients are limited. We performed scRNA‐seq on tumors and adjacent normal tissues from four Japanese CRC patients and identified a shared malignant cell cluster with high KCNQ1OT1 expression and reduced RASSF6 levels.
Sadahiro Iwabuchi   +15 more
wiley   +1 more source

Dinoflagellate mRNA is pervasively modified with m1A

open access: yesEMBO Reports
N(1)-methyladenosine (m(1)A) is a very rare RNA modification in mammalian mRNA, which occurs in sequences resembling the T-loop of tRNAs and may not have significant effects on gene expression. A new study in this issue now reports that m(1)A is abundant and dynamic in the 3′UTR of mRNAs of dinoflagellates, and could have an important role in post ...
Jianheng Fox Liu, Samie R Jaffrey
openaire   +2 more sources

GPRC5B Identified by m5C meRIP‐Seq Suppresses Apoptosis in Osteosarcoma Through NSUN2‐Mediated RNA Methylation

open access: yesCancer Science, Volume 117, Issue 5, Page 1322-1332, May 2026.
We performed the first transcriptome‐wide profiling of m5C modifications in osteosarcoma, analyzing four pairs of tumor and adjacent normal tissues. We revealed that NSUN2 suppresses apoptosis in osteosarcoma cells by promoting GPRC5B m5C modification and expression.
Zhenyi Chen   +10 more
wiley   +1 more source

Optimized workup of lymph nodes in regard to UICC classification of colorectal carcinoma

open access: yesHistopathology, Volume 88, Issue 6, Page 1250-1267, May 2026.
Treatment and outcome of colon cancer depend significantly on the histopathological examination of lymph nodes. Methodologically, stepwise sectioning and immunohistochemistry are the primary methods used. The extent of this examination is subject to debate but should be maintained at an adequate level in routine laboratory work.
Moritz Rust   +6 more
wiley   +1 more source

Controllability of Various Monetary Aggregates [PDF]

open access: yes
Analysis of the estimation performed indicates the need for adequate attention over the target aggregates. In the light of other policies undermining monetary control, it is worthwhile to ensure transparency on the central bank’s goal.central bank, money
Lamberte, Mario B.
core  

Overreliance on Orthographic Similarity in L2‐Japanese Conceptual Processing by L1‐Chinese Learners

open access: yesInternational Journal of Applied Linguistics, Volume 36, Issue 2, Page 1807-1820, May 2026.
ABSTRACT Orthographic and phonological similarities between first (L1) and second (L2) languages can facilitate L2 processing. Particularly, L1‐Chinese learners of L2‐Japanese can benefit from the shared morphosyllabic Chinese characters (Japanese kanji/Chinese hanzi) because of their similar orthographies.
Xuehan Zhao, Kexin Xiong, Sachiko Kiyama
wiley   +1 more source

In Vitro Metabolism and Analytical Characterization of SLU‐PP‐332 and SLU‐PP‐915: Novel Pan‐ERR Agonists With Doping Potential

open access: yesRapid Communications in Mass Spectrometry, Volume 40, Issue 8, 30 April 2026.
ABSTRACT Rationale Estrogen‐related receptor (ERR) agonists such as the drug candidates SLU‐PP‐332 and SLU‐PP‐915 are currently being investigated as exercise mimetics, given their ability to trigger human physiological processes similar to those initiated by actual physical activity.
Tristan Möller   +2 more
wiley   +1 more source

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