Results 131 to 140 of about 14,453 (241)
Journal of Cellular and Molecular MedicineResearch indicates that there are links between m6A, m5C and m1A modifications and the development of different types of tumours. However, it is not yet clear if these modifications are involved in the prognosis of LUAD. The TCGA‐LUAD dataset was used as
Chao Ma, Zhuoyu Gu, Yang Yang
semanticscholar +1 more source
Radical‐Based On‐Surface Transformation of Nonplanar Aromatics Into Nonbenzenoid Nanographenes
Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.Formation of radicals in nonplanar hydrocarbons through thermally induced dehydrogenation leads to molecular transformation via intramolecular radical‐based cyclization and dimerization, leading to formation of nonbenzenoid nanographenes. ABSTRACT On‐surface synthesis has emerged as a powerful tool for atomically precise C─C bond formation, enabling ...
Daniel Rothhardt +8 more
wiley +2 more sources
Updates on intratumoral therapies in melanoma
Cancer, Volume 132, Issue 13, 1 July 2026.Abstract Intratumoral therapies provide an opportunity for novel strategies in the management of advanced melanoma. These approaches deliver concentrated doses of therapeutic immune agents directly into individual tumor(s), achieving local tumor control and induction of systemic antitumor immune responses while minimizing the risk of immune‐related ...
Vincent T. Ma +12 more
wiley +1 more source
The role of m5C, m1A and m7G modifications in tumors of urinary system
Frontiers in Cell and Developmental BiologyMalignant tumors of the urinary system, such as kidney cancer, bladder cancer, and prostate cancer, remain a significant challenge despite the various treatment options available. Identifying therapeutic targets for urological tumors is crucial due to the potential for recurrence and metastasis.
Wei Xue +5 more
openaire +4 more sources
CNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.This study integrated multi‐omics data to analyze the synergistic effects of cellular senescence and RNA modifications on AD pathology. Transcriptome and proteome data were used to validate the stability of machine learning‐screened proteins and the model, while metabolomics data further revealed metabolic alterations during the progression of AD ...
Mengjie Tian +9 more
wiley +1 more source
N1-methylation of adenosine (m1A) in ND5 mRNA leads to complex I dysfunction in Alzheimer’s disease [PDF]
One mechanism of particular interest to regulate mRNA fate post-transcriptionally is mRNA modification. Especially the extent of m1A mRNA methylation is highly discussed due to methodological differences. However, one single m1A site in mitochondrial ND5
Wirtz Martin, Katja M. +18 more
core +2 more sources
Journal of Neuroendocrinology, Volume 38, Issue 7, July 2026.Abstract Introduction: VIPoma is an extremely rare functioning pancreatic neuroendocrine tumor. Therefore, data regarding treatment and outcome are very limited. Aim (s): This multicenter study aimed to analyze clinical characteristics, real‐world management, and outcomes of patients with VIPoma.
Detlef K. Bartsch +15 more
wiley +1 more source
Annals of the New York Academy of Sciences, Volume 1561, Issue 1, July 2026.This 15‐year bibliometric study (2009–2024) characterizes the global landscape of liquid–liquid phase separation (LLPS) in neurodegenerative diseases. We delineate the field's evolution from fundamental biophysics to clinical translation, emphasizing the liquid‐to‐solid transition of proteins like TDP‐43, tau, and α‐synuclein.
Chanyuan Zhang +6 more
wiley +1 more source