Results 141 to 150 of about 13,010 (203)

Real-world efficacy and toxicity of tebentafusp in metastatic uveal melanoma patients treated on the United Kingdom expanded access programme. [PDF]

Oncologist
Joseph M, Tharakan J, Proudfoot-Jones J, Sacco JJ, Furness A, McMahon D, Khoja L, Pallan L, Serra P, Ranatunge D, Oladipo B, Clements G, Mariappan L, Hennah L, Talbot T, Nobes J, Carter T, Shaw H, Nathan P.   +18 more
europepmc   +1 more source

Endogenous Biomarkers to Evaluate Transporter-Mediated Drug-Drug Interactions: Current Evidence, Impact on Clinical Pharmacology Strategy, Remaining Gaps, and Future Directions. [PDF]

J Clin Pharmacol
Russell LE, Huang F, Cheung KWK, Varma MVS, Panduga V.   +4 more
europepmc   +1 more source

MRI-derived T stage predicts nodal positivity on PSMA PET/CT in high-risk primary prostate cancer. [PDF]

Front Nucl Med
Courtney M, Whiriskey R, Johnston C, Sheehy N.   +3 more
europepmc   +1 more source

Molecular Subtype Identification and Prognostic Prediction of Pancreatic Cancer Based on m6A/m5C/m1A-Related Genes. [PDF]

J Cell Mol Med
Wang Y, Hong X, Cao D, Wang M, Tuergong A, Liu H, Guo Y, Ting X, Liu X, Huo X, Si W.   +10 more
europepmc   +1 more source

Targeting N¹-methyladenosine modification in osteoblasts through tRNA methyltransferase 10C reverses mitochondrial dysfunction and ameliorates osteoporosis. [PDF]

Signal Transduct Target Ther
Sun H, Wang W, Zhang C, Zhang T, Yang X, Feng Y, Shan L, Yang Z, Zhang Y, Liu S, Wang W, Wang J, Hou X, Feng S.   +13 more
europepmc   +1 more source

Advances in the Structural and Functional Understanding of m1A RNA Modification

RNA modification is a co-or post-transcriptional process by which specific nucleotides are chemically altered by enzymes after their initial incorporation into the RNA chain, expanding the chemical and functional diversity of RNAs. Our understanding of RNA modifications has changed dramatically in recent years.
Smoczynski, Jakub, Yared, Marcel-Joseph, Meynier, Vincent, Barraud, Pierre, Tisné, Carine   +4 more
openaire   +1 more source

CRISPR technologies for detecting DNA and RNA methylation: Mechanisms, platforms, and translational opportunities. [PDF]

Bioeng Transl Med
Chen K, Yang B, Sang R, Chen W, Xiang T, Deng F.   +5 more
europepmc   +1 more source

RNA modifications and RNA-binding proteins: interactions, regulation, and new avenues for therapeutic modulation. [PDF]

RSC Chem Biol
Vega-Hernández G, Garner AL.
europepmc   +1 more source

TRMT6/61A-mediated tRNA m1A methylation promotes codon-dependent TAB2 translation and drives AML progression. [PDF]

Mol Med
Jia Z, Wu X, Ouyang A, ChengZhang, Liu Y, Wu G, Chen Z, Li S.   +7 more
europepmc   +1 more source

Modtector: ultra-fast modification signal mining on mapped sequencing reads. [PDF]

Bioinformatics
Zhou T, Hong Y, Li P, Liu X, Zhang J, Wang X, Li A, Sun L.   +7 more
europepmc   +1 more source