Results 11 to 20 of about 855,003 (301)

Nanopore direct RNA sequencing maps the complexity of Arabidopsis mRNA processing and m6A modification [PDF]

open access: yes, 2020
Understanding genome organization and gene regulation requires insight into RNA transcription, processing and modification. We adapted nanopore direct RNA sequencing to examine RNA from a wild-type accession of the model plant Arabidopsis thaliana and a ...
Barton, Geoffrey J.   +8 more
core   +3 more sources

Novel Modifications in RNA [PDF]

open access: yesACS Chemical Biology, 2011
The past several years have seen numerous reports of new chemical modifications for use in RNA. In addition, in that time period, we have seen the discovery of several previously unknown naturally occurring modifications that impart novel properties on the parent RNAs.
Kelly, Phelps   +2 more
openaire   +2 more sources

THE FREQUENCY AND FITNESS OF m6A-ASSOCIATED VARIANTS COULD BE MODULATED BY THE THERMODYNAMIC STABILITY OF AN OVERLAPPING G-QUADRUPLEX

open access: yesSabiad, 2023
Objective: Post-transcriptional modifications like m6A (N6-methyladenosine) and secondary structures like G-quadruplex (G4) are formations that play a vital role in RNA processing. Their synergy also has functional consequences.
Çağrı Güleç
doaj   +1 more source

The RNA modification database [PDF]

open access: yesNucleic Acids Research, 1996
The RNA modification database provides a comprehensive listing of posttranscriptionally modified nucleosides from all RNAs, and is maintained as an updated version of the initial printed report [Limbach,P.A., Crain,P.F. and McCloskey,J.A. (1994)Nucleic Acids Res. , 22, 2183-2196].
P F, Crain, J A, McCloskey
openaire   +4 more sources

No evidence for age-related differences in mitochondrial RNA quality in the female germline

open access: yesReproduction and Fertility, 2022
Mitochondrial quality is implicated as a contributor to declining fertility with aging. We investigated mitochondrial transcripts in oocytes and their associated cumulus cells from mice of different ages using RNA-seq.
Fiona Hartley   +7 more
doaj   +1 more source

Role of m6A in Embryonic Stem Cell Differentiation and in Gametogenesis

open access: yesEpigenomes, 2020
The rising field of RNA modifications is stimulating massive research nowadays. m6A, the most abundant mRNA modification is highly conserved during evolution.
Lior Lasman   +2 more
doaj   +1 more source

RNA Modification in Carcinogenesis and Development of Gastric Cancer

open access: yesZhongliu Fangzhi Yanjiu, 2023
The occurrence of gastric cancer is closely related to environmental, genetic, and epigenetic factors. Currently, RNA modification is a research frontier and hotspot in the field of epigenetics.
XU Jiawen, WANG Qiang, WANG Shouyu
doaj   +1 more source

Identification of a novel methyltransferase, Bmt2, responsible for the N-1-methyl-adenosine base modification of 25S rRNA in "Saccharomyces cerevisiae" [PDF]

open access: yes, 2013
The 25S rRNA of yeast contains several base modifications in the functionally important regions. The enzymes responsible for most of these base modifications remained unknown.
Entian, Karl-Dieter   +3 more
core   +1 more source

Detection of RNA modifications [PDF]

open access: yesRNA Biology, 2010
RNA nucleotide modifications are typically of low abundance and frequently go unnoticed by standard detection methods of molecular biology and cell biology. With a burst of knowledge intruding from such diverse areas as genomics, structural biology, regulation of gene expression and immunology, it becomes increasingly clear that many exciting functions
Stefanie, Kellner   +2 more
openaire   +2 more sources

It’s the Little Things (in Viral RNA)

open access: yesmBio, 2020
Chemical modifications of viral RNA are an integral part of the viral life cycle and are present in most classes of viruses. To date, more than 170 RNA modifications have been discovered in all types of cellular RNA.
Jiří František Potužník   +1 more
doaj   +1 more source

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