Results 81 to 90 of about 29,101,112 (306)
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Bursts in m-metric array codes
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Let F2(m) be a finite field of 2m elements, λ and k be integers satisfying λ, k ≥ 2 and denote R = F2(m)[u]/(u2λ). Let δ, α ∈ F2(m)×.
Yuan Cao +4 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Let $ p $ be a prime and $ m $ a positive integer. This paper investigates cyclic and self-dual codes of length $ n $ over the local Frobenius non-chain ring $ R = \mathrm{GR}(p^3, m)[v] $, with $ v^2 = p^2 \alpha $, $ \alpha \in \mathbb{F}^*_{p^m ...
Sami Alabiad, Alhanouf Ali Alhomaidhi
doaj +1 more source
Combined Source-Channel Coding of Images under Power and Bandwidth Constraints
This paper proposes a framework for combined source-channel coding for a power and bandwidth constrained noisy channel. The framework is applied to progressive image transmission using constant envelope M-ary phase shift key (M-PSK) signaling over an ...
Marc Fossorier +2 more
doaj +1 more source
On the Hamming Distances of Constacyclic Codes of Length 5
Let $p$ be a prime, $s$ , $m$ be positive integers, and $\lambda $ be a nonzero element of the finite field $\mathbb {F}_{p^{m}}$ . In this paper, the algebraic structures of constacyclic codes of length $5~p^{s}~(p\neq 5)$ are obtained, which ...
Hai Q. Dinh +2 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source

