Results 41 to 50 of about 1,757 (195)

Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy

open access: yesAdvanced Science, EarlyView.
Autoantibodies against fibroblast growth factor receptor 3 (FGFR3) are identified as pathogenic drivers of pain in small fiber neuropathy. By binding to sensory neurons in dorsal root ganglia, FGFR3 autoantibodies activate MAPK signaling and induce hyperexcitability and mechanical hypersensitivity, establishing FGFR3 autoantibodies as a therapeutic ...
Lyuba Y. Salih   +12 more
wiley   +1 more source

Stellar Cycle and Evolution of Polar Spots in an M+WD Binary

open access: yesThe Astrophysical Journal
Stellar activity cycles reveal continuous relaxation and induction of magnetic fields. The activity cycle is typically traced through the observation of cyclic variations in total brightness or Ca H&K emission flux of stars, as well as cyclic variations ...
Xinlin Zhao   +7 more
doaj   +1 more source

Single‐Cell Metabolic Imaging and Digital Scoring of Fat Tissue Remodeling by Label‐Free Metabolic Microscopy

open access: yesAdvanced Science, EarlyView.
Mid‐infrared optoacoustic microscopy (MiROM) acquires lipid‐ and protein‐ associated vibrational contrast in intact fat tissue without dyes, preserving native tissue architecture. Through lateral and axial segmentation, MiROM tracks intrinsic intracellular changes during postnatal remodeling. A quantitative spatial analysis tool (Q‐SAT) maps white‐ and
Myeongseop Kim   +7 more
wiley   +1 more source

The Importance of the Upper Atmosphere to CO/O2 Runaway on Habitable Planets Orbiting Low-mass Stars

open access: yesThe Astrophysical Journal Letters, 2023
Efforts to spectrally characterize the atmospheric compositions of temperate terrestrial exoplanets orbiting M dwarf stars with JWST are now underway.
Sukrit Ranjan   +4 more
doaj   +1 more source

Synthetic activity indicators for M-type dwarf stars [PDF]

open access: yesProceedings of the International Astronomical Union, 2015
AbstractHere, we present a set of time-dependent 3D RMHD simulations of a M-dwarf star representative of AD Leo, which extend from the upper convection zone into the chromosphere. The 3D model atmospheres are characterized by a very dynamic and intermittent structure on small spatial and temporal scales and a wealth of physical processes, which by ...
Wedemeyer, Sven, Ludwig, Hans-Günter
openaire   +2 more sources

NuSAP Safeguards Centriole Integrity to Mediate CEP57‐CEP152 Torus Recruitment for Proper Engagement

open access: yesAdvanced Science, EarlyView.
This study reveals a novel role for the microtubule stabilizer NuSAP at centrioles. NuSAP depletion destabilizes the centriole's tubulin structure, causing premature disengagement, PCM defects, and mis‐localization of the CEP57‐CEP63‐CEP152 complex. By reinforcing centriole architecture, NuSAP enables early CEP57 loading and initiates a newly proposed ...
Shiyu Zhang   +8 more
wiley   +1 more source

EDGE-INFERNO: Simulating Every Observable Star in Faint Dwarf Galaxies and Their Consequences for Resolved-star Photometric Surveys

open access: yesThe Astrophysical Journal
Interpretation of data from faint dwarf galaxies is made challenging by observations limited to only the brightest stars. We present a major improvement to tackle this challenge by undertaking zoomed cosmological simulations that resolve the evolution of
Eric P. Andersson   +6 more
doaj   +1 more source

A Nearby Isolated Dwarf: Star Formation and Structure of ESO 006–001

open access: yesThe Astrophysical Journal, 2023
Observations with the Hubble Space Telescope unexpectedly revealed that the dwarf galaxy ESO 006–001 is a near neighbor to the Local Group at a distance of 2.70 ± 0.11 Mpc.
Lidia N. Makarova   +6 more
doaj   +1 more source

Spatial‐Wavelength Multiplexing Error‐Controlled Photonic Analog Computing System

open access: yesAdvanced Science, EarlyView.
A novel photonic integrated circuit prototype implementing the concept of general‐purpose analog computing and demonstrate its capability in radio frequency applications. The chip features a multichannel architecture and performs fully optical analog computation with frequency‐domain parallel processing. An FPGA‐based error‐correction algorithm aims to
Tao Zhu   +15 more
wiley   +1 more source

Precise Mass, Orbital Motion, and Stellar Properties of the M-dwarf Binary LP 349−25AB

open access: yesThe Astrophysical Journal
LP 349−25 is a well-studied close stellar binary system comprised of two late M dwarf stars, where both stars are close to the limit between star and brown dwarf. This system was previously identified as a source of gigahertz radio emission.
Salvador Curiel   +3 more
doaj   +1 more source

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