Results 261 to 270 of about 24,445,127 (303)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Modular Access to α-Tertiary Amines: Electrochemical Tandem Di-Functionalization of Olefins With Ammonia Surrogates and Amino Acids. [PDF]

Angew Chem Int Ed Engl
Ghosh A, Tarun, Peters SE, Ackermann L, Banerjee D.   +4 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Using cognitive interviews with children to test the content validity of a paediatric patient reported experience measure. [PDF]

BMJ Paediatr Open
Barr KR, Fortunati E, Studniberg Z, Nikolovski J, White L, Elliott S, McCartney L, Smith-McCue D, Noah M, Swaminathan G, John JR, Treadgold C, Hall A, Dadich A, Vernon B, Toscano E, Hiscock H, Chow J, Johnston L, Whitehead L, Foster M, Sung V, Eapen V.   +22 more
europepmc   +1 more source

Multi-omic analysis of jaw-bone periosteum identifies the role of macrophage-derived SPP1 in Ctsk⁺Fmod⁺ periosteal cells. [PDF]

Bone Res
Yi Z, Liu Y, Wang J, Deng C, Jin Y, Qu Y, Hu C, Man Y.   +7 more
europepmc   +1 more source

Serum vitamin D and fracture risk in children and adolescents: A systematic review and meta-analysis highlighting age and altitude as key moderators. [PDF]

Exp Ther Med
Ma J, Tang B, Zhai Z, Dang Z.
europepmc   +1 more source

Multimodality evaluation of bilateral parotid oncocytomas: A rare case report and literature review. [PDF]

Radiol Case Rep
Anwar S, Mubarak F, Mahmood A, Ahmed M.
europepmc   +1 more source

Belowground bud bank depletion constrains productivity recovery in long established perennial pastures despite nitrogen enrichment. [PDF]

Front Plant Sci
He K, He L, Dang H, Li J, Wang Q, Zhou Q, Wang J, Wei X.   +7 more
europepmc   +1 more source