Results 91 to 100 of about 274,237 (307)

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

Advanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu, Cheng Kiu Ho, Jitao Liu, Lei Cui, Yangfeng Hou, Cai Liang, Wenchu Ye, Randolph H. L. Wong, Shohei Hori, Bin Zhou, Kathy O. Lui   +10 more
wiley   +1 more source

Comparative Assessment of Manual Material Handling Using the Two Methods of NIOSH Lifting Equation in a Tile Manufacturing Company MAC and Revised

Salāmat-i kār-i Īrān, 2013
Background and aims : Manual material handling (MMH) can be lead to work-related musculoskeletal disorders and one of the most common disorders due to MMH tasks is low back pain.
A Dormohammadi, M Motamedzade, H Amjad sardrudi, E Zarei, M Asghari, S Musavi   +5 more
doaj  

Optimized Multiplier Architectures for Enhanced Performance and Efficiency in MAC Units

International Journal of Emerging Research in Engineering, Science, and Management
This paper investigated the performance of Vedic multipliers in a 32-bit Multiplier-Accumulator Unit (MAC) by comparing Urdhva Tiryakbhyam and Nikhilam Sutras with various adder architectures. The goal was to identify the optimal combination of speed and
G Priyanka, N Gireesh, S Hemachandra
doaj   +1 more source

پیش‌بینی نتایج BYK-mac-i در اندازه‌گیری ویژگی دانه‌ای‌شدن در پوشش‌های متالیک با استفاده از اسکنر و روش‌های تحلیل بافتار [PDF]

علوم و فناوری رنگ
پوشش‌های متالیک به دلیل ویژگی‌های دیداری جذاب، در صنایع مختلفی از جمله خودروسازی و دکوراسیون مورد استفاده قرار می‌گیرند. ارزیابی دانه‌ای‌شدن بافتار این پوشش‌ها نقش مهمی در کنترل کیفیت آن‌ها دارد. در این پژوهش، روش‌های مختلف پردازش تصویر شامل تبدیل فوریه،
فاطمه ملک پور, سعیده گرجی‌کندی, محسن محسنی   +2 more
doaj   +1 more source

An On‐Demand Neuromorphic Vision System Enabled by a Multi‐Paradigm Neuromorphic Device and Hierarchical Reconfigurability Designed from Device to System Level

Advanced Science, EarlyView.
An on‐demand ultra‐reconfigurable intelligent vision system with hierarchical reconfigurability from device to system levels is demonstrated. Through co‐design of a multi‐paradigm device, reconfigurable circuits, and adaptive system architecture/algorithms, the system enables seamless switching among spiking, non‐spiking, neuromorphic imaging (NI), and
Biyi Jiang, Jiayi Xu, Liang Ran, Xinhe Feng, Khalil Harrabi, Yida Li, Longyang Lin, Feichi Zhou   +7 more
wiley   +1 more source

Development of rapid guidelines: 1. Systematic survey of current practices and methods

Health Research Policy and Systems, 2018
Background Guidelines in the healthcare field generally should contain evidence-based recommendations to inform healthcare decisions. Guidelines often require 2 years or more to develop, but certain circumstances necessitate the development of rapid ...
Sergio C. Kowalski, Rebecca L. Morgan, Maicon Falavigna, Iván D. Florez, Itziar Etxeandia-Ikobaltzeta, Wojtek Wiercioch, Yuan Zhang, Faria Sakhia, Liudmila Ivanova, Nancy Santesso, Holger J. Schünemann   +10 more
doaj   +1 more source

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

Effect of epidural administration of lidocaine, fentanyl and their combination on the minimum alveolar concentration of halothane in dogs

Veterinární Medicína, 2004
The efficacy of lidocaine, fentanyl, combination of both (2 mg/kg of lidocaine, along with fentanyl in the dose of 0.005 mg/kg) and saline (as a control) administered epidurally to 40 healthy dogs was under investigation, regarding their influence on ...
P. Rauser, L. Lexmaulova, M. Vlasin, T. Fichtel, J. Lorenzova   +4 more
doaj   +1 more source

The Summer Place For Your Boy

, 2015
Mac Levy ...
Mac Levy
core  

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

Advanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng, Xia Yang, Lin An, Xue‐Yu Wang, Ming‐Rui Wang, Zhuo‐Hong Cai, Cai‐Jun Xie, Li‐Jun Qiao, You‐Bi Shen, Xi‐Min Liang, Rong Zhang, Cai‐Yan Wang, Zhong‐Qiu Liu, Rong‐Rong Zhang   +13 more
wiley   +1 more source