Results 171 to 180 of about 1,445,204 (316)

Impact of Left Atrial Strain on Severe Mitral Regurgitation Due to Mitral Annular Calcification. [PDF]

JACC Adv
Al Zein M, Okushi Y, Unai S, Pettersson GB, Gillinov AM, Grimm RA, Griffin BP, Xu B.   +7 more
europepmc   +1 more source

PD‐L1‐Binding Antigen Presenters: Redirecting Vaccine‐Induced Antibodies for Cancer Immunotherapy

Advanced Science, EarlyView.
The PBAP‐gE complex anchors gE antigen to PD‐L1 on tumor cells. Vaccine‐induced anti‐gE antibodies simultaneously engage FcγRIIIa on NK cells and tumor‐bound PBAP‐gE, triggering NK cell activation and antibody‐dependent cellular cytotoxicity, thereby selectively eliminating PD‐L1–expressing tumor cells.
Huixin Gao, Lijuan Lu, Xiaoxiao Xiong, Yi Li, Donghui Hu, Duo Zhang, Zhiwei Feng, Cong Liu, Nannan Liu, Xiaoli Li, Jizhou Tan, Ting Liu, Ling Peng, Lu Lu, Huiyi Feng, Yan Zhong, Guisen Tan, Zhicheng Zhang, Liqin Huang, Chao Su, Ying Xue, Shuo Song, Wenxia Fan, Wei Wang, Fan Zou   +24 more
wiley   +1 more source

Enhanced colorectal gland segmentation through multi-scale attention and contextual feature fusion. [PDF]

Sci Rep
B K P, N L, Ajibesin AA.
europepmc   +1 more source

Resilient Calvarial Bone Marrow Supports Retinal Repair in Type 2 Diabetes

Advanced Science, EarlyView.
Skull bone (calvarium) marrow in diabetic mice stay structurally intact and keeps making blood cells, unlike the bone marrow of the leg bones. The skull marrow is exposed to cerebrospinal fluid (CSF), which contains protective molecules called oxysterols.
Bright Asare‐Bediako, Sergio Li Calzi, Julia G. Behnsen, Ram Prasad, Magdalena Blaszkiewicz, Yvonne Adu‐Rutledge, Robert F. Rosencrans, Jason L. Floyd, Ashley Rennhack, Denise Stanford, Anna Lin, Todd A. Lydic, Carl M. Sheridan, Michael E. Boulton, Kristy L. Townsend, Julia V. Busik, Maria B. Grant   +16 more
wiley   +1 more source

Mitral Annular Calcification Score Determined by 3-D Transesophageal Echocardiography vs Cardiac Computed Tomography. [PDF]

JACC Adv
Quelal Analuisa K, Challa A, Lane C, Al-Abcha A, George I, Whisenant BK, Satler LF, Makkar RR, Mahoney PD, Zahr FE, Golwala H, Shah PB, Inglessis-Azuaje I, Waggoner T, Muhammad K, Eng MH, Kaptzan T, Lewis B, Thaden J, Bird J, Williamson EE, Collins J, Eleid MF, Oh JK, Guerrero ME.   +24 more
europepmc   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

An ns-3 Evaluation Framework for Receiver-Initiated MAC Protocols with Configurable Enhancement Modules Across Various Network Scenarios. [PDF]

Sensors (Basel)
Murata T, Sakamoto S, Kawanami T.
europepmc   +1 more source

An On‐Demand Neuromorphic Vision System Enabled by a Multi‐Paradigm Neuromorphic Device and Hierarchical Reconfigurability Designed from Device to System Level

Advanced Science, EarlyView.
An on‐demand ultra‐reconfigurable intelligent vision system with hierarchical reconfigurability from device to system levels is demonstrated. Through co‐design of a multi‐paradigm device, reconfigurable circuits, and adaptive system architecture/algorithms, the system enables seamless switching among spiking, non‐spiking, neuromorphic imaging (NI), and
Biyi Jiang, Jiayi Xu, Liang Ran, Xinhe Feng, Khalil Harrabi, Yida Li, Longyang Lin, Feichi Zhou   +7 more
wiley   +1 more source

Bacterial-archaeal co-occurrence in honey bee gut microbiomes across host species and management regimes. [PDF]

PLoS One
Ying JP, Zou YF, Jiang T, Chang JL.
europepmc   +1 more source

A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1.

Journal of Clinical Investigation, 2012
J. Pillay, V. Kamp, E. van Hoffen, T. Visser, T. Tak, J. Lammers, L. Ulfman, L. Leenen, P. Pickkers, L. Koenderman   +9 more
semanticscholar   +1 more source