Results 91 to 100 of about 265,670 (337)
Advanced Materials Technologies, EarlyView.The hydroporator platform employs controlled hydrodynamic deformation for efficient mRNA and CRISPR/Cas9 delivery into primary human T cells, enabling allogeneic CAR‐T cell manufacturing. It preserves cell functionality and drives potent gene editing, CAR expression, and tumor cytotoxicity, while feature‐based analysis links these functional outcomes ...
Soohyun Jeon +6 more
wiley +1 more source
Advanced Science, EarlyView.Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance +17 more
wiley +1 more source
CAC-MAC: A Cross-Layer Adaptive Cooperative MAC for Wireless Ad Hoc Networks
International Journal of Distributed Sensor Networks, 2012 Cooperative communication has been recently proposed as a way to mitigate fading in wireless networks. A cross-layer adaptive cooperative MAC (CAC-MAC) protocol for IEEE 802.11 DCF-based wireless ad hoc networks is proposed.
Chunguang Shi +4 more
doaj +1 more source
Advanced Science, EarlyView.Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider +20 more
wiley +1 more source
A Scalable MAC Protocol Supporting Simple Multimedia Traffic QoS in WSNs
International Journal of Distributed Sensor Networks, 2011 Wireless sensor networks (WSNs) are a vibrant research field for the last several years. Especially, design of MAC protocols supporting multimedia traffic QoS is recent challenging work.
JeongSeok On, HahnEarl Jeon, Jaiyong Lee
doaj +1 more source
Advanced Science, EarlyView.Dendritic cells (DC) vaccine is an important type of vaccines. However, the limited efficacy of DC vaccines hinders their widely application. This study redefines DC vaccines and provides a new DC‐BC vaccine that have much better therapeutic efficacy.
Xiangxiang Xu +11 more
wiley +1 more source
A Fair Cooperative MAC Protocol in IEEE 802.11 WLAN
Future Internet, 2018 Cooperative communication techniques have recently enabled wireless technologies to overcome their challenges. The main objective of these techniques is to improve resource allocation.
Seyed Davoud Mousavi +4 more
doaj +1 more source
LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1
Advanced Science, EarlyView.LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li +12 more
wiley +1 more source
Advanced Science, EarlyView.An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang +10 more
wiley +1 more source
Advanced Science, EarlyView.This work establishes a standardized, high‐resolution spatial transcriptomics workflow for characterizing host responses to biomaterial implants. Using the 10× Xenium platform, the pipeline integrates spatial mapping, subclustering, and functional enrichment to resolve immune and stromal cell organization at single‐cell resolution, enabling ...
Alex H.P. Chan +7 more
wiley +1 more source