Results 141 to 150 of about 265,670 (337)

In Vivo CRISPR Screening Identifies the Glutamate Receptor GRIA2 as Promoting Peritoneal Metastasis of Gastric Cancer via Calcium‐Dependent β‐Catenin Activation

open access: yesAdvanced Science, EarlyView.
We identified GRIA2 as a critical driver of gastric cancer peritoneal metastasis through in vivo CRISPR screening. Mechanistically, GRIA2‐mediated calcium influx inhibits GSK3β and activates Wnt/β‐catenin signaling, driven by glutamate from cancer‐associated fibroblasts.
Jie Sun   +13 more
wiley   +1 more source

MAC protocol with grouping awareness GMAC for large scale Internet-of-Things network. [PDF]

open access: yesPeerJ Comput Sci, 2021
Sameer Sadeq A   +6 more
europepmc   +1 more source

ZMAT1 Promotes Osteoclastogenesis Through TRIM46 Mediated YAP1 Degradation and Inhibits Osteoblastogenesis

open access: yesAdvanced Science, EarlyView.
Zmat1 deficiency mitigates pathological bone loss by impairing osteoclastogenesis and promoting osteoblastogenesis. Mechanistically, in osteoclasts, Zmat1 loss relieves transcriptional repression of the E3 ligase TRIM46, promoting YAP1 degradation and inhibiting osteoclastogenic genes.
Xinyu Chang   +13 more
wiley   +1 more source

EasyMap MAC Protocol

open access: yes, 2013
EasyMap MAC protocol is a new and simple Medium Access Control protocol, which allows a wireless sensor network to operate with low power and good throughput. This new protocol is specially designed for the applications which collect data on a relatively regular schedule and which are required to last for a long period of time.
openaire   +1 more source

Cryoablation Activates the cGAS–STING‐CXCL10 Axis in Macrophages to Enhance Anti‐Tumor Immunity in NSCLC

open access: yesAdvanced Science, EarlyView.
Tumor dsDNA released by cryoablation is taken up by macrophages, activating the cGAS‐STING signaling pathway. This leads to an expansion of the CXCL10+ macrophage pool and increased secretion of CXCL10, which in turn recruits CXCR3+ T cells from draining lymph nodes into the tumor microenvironment to exert anti‐tumor effects.
Xinxin Zhi   +17 more
wiley   +1 more source

Energy-Aware QoS MAC Protocol Based on Prioritized-Data and Multi-Hop Routing for Wireless Sensor Networks. [PDF]

open access: yesSensors (Basel), 2022
Sakib AN   +5 more
europepmc   +1 more source

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