Results 61 to 70 of about 1,449,650 (280)

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

open access: yesAdvanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren   +6 more
wiley   +1 more source

Rule and perception based MAC protocol for UAN

open access: yesTongxin xuebao, 2022
Aiming at the problem of low channel utilization and network throughput resulted by RTS/CTS handshakes in the conventional media access control (MAC) protocol for underwater acoustic network (UAN), a rule and perception based (RP-MAC) MAC protocol was ...
Chong LI   +3 more
doaj   +2 more sources

The energy-efficient MDA-SMAC protocol for wireless sensor networks

open access: yesEURASIP Journal on Wireless Communications and Networking, 2020
Nodes in original S-MAC protocol just can visit the channel in the scheduling and listening stage. The working schema may result in data latency and high conflict. To solve those above problems, we split scheduling duty into multiple micro-duties.
Ke Wang   +4 more
doaj   +1 more source

Robotics in Ionizing Radiation Environments: Vulnerabilities, Hardening, and Future Directions

open access: yesAdvanced Robotics Research, EarlyView.
Radiation exposure causes cumulative degradation in robotic sensors, actuators, and electronic logic, often leading to undetected failures. This study maps component vulnerabilities, evaluates hardening and shielding strategies, and identifies testing gaps that must be addressed to enable next‐generation radiation‐tolerant robotic systems.
Francis A. K. Djirackor   +4 more
wiley   +1 more source

A Dynamic Traffic-Aware Duty Cycle Adjustment MAC Protocol for Energy Conserving in Wireless Sensor Networks

open access: yesInternational Journal of Distributed Sensor Networks, 2012
Wireless sensors are battery-limited sensing and computing devices. How to prolong the lifetime of wireless sensors becomes an important issue. In order to reduce the energy consumptions when nodes are in idle listening, duty-cycle-based MAC protocols ...
Tz-Heng Hsu   +3 more
doaj   +1 more source

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

open access: yesAdvanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao   +27 more
wiley   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

open access: yesAdvanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin   +20 more
wiley   +1 more source

Energy Efficient MAC Protocol for Low-Energy Critical Infrastructure Monitoring Networks Using Wakeup Radio

open access: yesInternational Journal of Distributed Sensor Networks, 2012
Critical infrastructure monitoring applications are rapidly increasing. Application requirements include reliable data transfer, energy efficiency, and long deployment lifetime.
Niamat Ullah   +3 more
doaj   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

open access: yesAdvanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He   +10 more
wiley   +1 more source

Neuromorphic Near‐Sensor and In‐Sensor Computing Enabled by Next‐Generation Material‐Based Sensors

open access: yesAdvanced Science, EarlyView.
This Review presents a structural framework that classifies neuromorphic sensing into near‐sensor and in‐sensor architectures, clarifying physical coupling between sensing and computation. The framework connects neural and synaptic device functions with recent advances in optical, mechanical, and chemical sensing, compares energy consumption and ...
Su Yeon Jung   +7 more
wiley   +1 more source

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