The Efficient Synthesis and Anti-Fatigue Activity Evaluation of Macamides: The Unique Bioactive Compounds in Maca [PDF]
Molecules, 2023 Macamides are a class of amide alkaloids that are only found in maca and are widely considered to be its bioactive marker compounds. More than thirty macamide monomers have been identified in recent years; however, it is difficult to obtain a single ...
Tao Liu, Xiaobao Jin, Hui Yin
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Macamides as Potential Therapeutic Agents in Neurological Disorders [PDF]
Neurology InternationalTherapeutic treatment of nervous system disorders has represented one of the significant challenges in medicine for the past several decades. Technological and medical advances have made it possible to recognize different neurological disorders, which ...
Karin J Vera-López +2 more
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Deep Eutectic Solvent-Based Ultrasound-Assisted Strategy for Simultaneous Extraction of Five Macamides from Lepidium meyenii Walp and In Vitro Bioactivities [PDF]
Foods, 2023 This study aimed to develop an integrated approach of deep eutectic solvent-based ultrasound-assisted extraction (DES–UAE) to simultaneously extract five major bioactive macamides from the roots of Lepidium meyenii Walp.
Keke Li +4 more
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Comprehensive Profiling of Macamides and Fatty Acid Derivatives in Maca with Different Postharvest Drying Processes Using UPLC-QTOF-MS [PDF]
ACS Omega, 2021 Chen Xia, Junlin Deng, Yu Pan
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Anticonvulsant Effects of Synthetic N-(3-Methoxybenzyl)oleamide and N-(3-Methoxybenzyl)linoleamide Macamides: An In Silico and In Vivo Study [PDF]
MoleculesEpilepsy is a chronic neurological disorder that affects nearly 50 million people worldwide. Experimental evidence suggests that epileptic neurons are linked to the endocannabinoid system and that inhibition of the FAAH enzyme could have neuroprotective ...
Karin Jannet Vera-López +7 more
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Using Immunoliposomes as Carriers to Enhance the Therapeutic Effectiveness of Macamide N-3-Methoxybenzyl-Linoleamide [PDF]
Neurology InternationalBackground/Objectives: Epilepsy is one of the most common chronic neurological disorders, characterized by alterations in neuronal electrical activity that result in recurrent seizures and involuntary body movements.
Karin J. Vera-López +3 more
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Exploring the chemical and pharmacological variability of Lepidium meyenii: a comprehensive review of the effects of maca [PDF]
Frontiers in PharmacologyMaca (Lepidium meyenii), a biennial herbaceous plant indigenous to the Andes Mountains, has a rich history of traditional use for its purported health benefits.
Norka Ulloa del Carpio +8 more
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Maca (Lepidium meyenii) as a Functional Food and Dietary Supplement: A Review on Analytical Studies [PDF]
FoodsMaca (Lepidium meyenii Walp.), a Brassicaceae species native to the high Andes of Peru, has gained global attention as a functional food and herbal medicinal product due to its endocrine-modulating, fertility-enhancing, and neuroprotective properties ...
Andreas Wasilewicz, Ulrike Grienke
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The Effects of Maca (Lepidium meyenii Walp) on Cellular Oxidative Stress: A Systematic Review and Meta-Analysis [PDF]
AntioxidantsLepidium meyenii Walp (LmW) or Maca, including its bioactive components such as macamides, among others, has demonstrated antioxidant effects. However, the effect size (ES) of LmW on oxidative stress has not been qualitatively described and calculated ...
Álvaro Huerta Ojeda +8 more
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Quantitative Determination of 15 Active Components in Lepidium meyenii with UHPLC-PDA and GC-MS [PDF]
Journal of Analytical Methods in Chemistry, 2021 In this study, a method using ultrahigh-performance liquid chromatography with photodiode array (UHPLC-PDA) was established and validated for the simultaneous quantification of 10 active components, including eight macamides and two glucosinolates, in ...
Yao-qing Xu +8 more
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