Results 211 to 220 of about 79,205 (258)

Mitochondrial Fusion and Fission in Age‐Related Cardio‐Cerebral Diseases: Mechanisms and Interventions

Aging Cell, Volume 25, Issue 10, October 2026.
Mitochondrial fission‐fusion imbalance contributes to age‐related cardio‐cerebral diseases like Alzheimer's disease, Parkinson's disease, Cerebral Infarction, Arteriosclerosis, Myocardial Infarction, Cardiac valve disease, Hypertension, and Cardiomyopathy. This review summarizes its regulatory mechanisms and interventions.
Yuyao Yin, Zijian Li
wiley   +1 more source

Challenges in predicting chromatin accessibility differences between species. [PDF]

NAR Genom Bioinform
Stephen AZM, Raje A, Sestili HH, Wirthlin ME, Lawler AJ, Brown AR, Ma J, Stauffer WR, Pfenning AR, Kaplow IM.   +9 more
europepmc   +1 more source

uPAR‐Targeting T Cell Engager Exerts Senolytic Effects in Mice and Non‐Human Primates With Serum Aminotransferase Activity as a Safety Monitor

Aging Cell, Volume 25, Issue 10, October 2026.
GFD‐CD3, a uPAR‐targeting T‐cell engager, effectively cleared senescent cells and mitigated age‐related pathologies with a favorable safety profile under transaminase‐guided monitoring. ABSTRACT Senolytic CAR‐T cells targeting uPAR induce dose‐dependent toxicities.
Jian Deng, Xiaozhu Zeng, Jing Guo, Lihong Li, Shirui Zou, Nan Liu, Shuai He, Lanzhen Yan, Qiong Wang, Yongjie Zhu, Ben Wang, Dong Yang, Longbao Lv, Xudong Zhao   +13 more
wiley   +1 more source

A <i>WHRN</i> mutation impacts ocular morphology in rhesus macaques. [PDF]

Front Cell Dev Biol
Ripolles-Garcia A, Raposo A, Le SM, Shim J, Park S, Roszak K, Lin KH, Khan M, Lee S, Thienpaitoon R, Gao L, Wang J, Knipe MF, Stout T, Rogers J, Chen R, Moshiri A, Thomasy SM.   +17 more
europepmc   +1 more source

Nonpathogenic SIV Infection in Sooty Mangabeys Is Characterized by a Lack of Activation and Expansion of Monocytes

Journal of Medical Primatology, Volume 55, Issue 5, October 2026.
ABSTRACT Introduction Natural hosts of simian immunodeficiency virus (SIV), including sooty mangabeys (SMs), maintain high viremia without progressing to AIDS and AIDS‐associated histopathogenesis. The mechanisms underlying this protection and lack of pathogenesis remain incompletely understood, particularly in relation to monocyte/macrophage ...
Caroline Soulas, Hai Duc Nguyen, Summer Siddiqui, Natalie Stahr, Tricia H. Burdo, Francis J. Novembre, Woong‐Ki Kim, Kenneth C. Williams   +7 more
wiley   +1 more source

Realistic monkey body animation reveals an uncanny valley in macaque body perception. [PDF]

PLoS Biol
Martini LM, Bognár A, Vogels R, Giese MA.   +3 more
europepmc   +1 more source

Spontaneous Hepatobiliary Disease in a Breeding Colony of Aotus spp.

Journal of Medical Primatology, Volume 55, Issue 5, October 2026.
ABSTRACT Background Owl monkeys are nonhuman primate species in the genus Aotus. The Michale E. Keeling Center for Comparative Medicine and Research maintains an Owl Monkey Breeding and Research Resource composed of four species of owl monkeys: Aotus nancymai, A. vociferans, A. azarae, and A. griseimembra.
M. E. Hensel, G. W. Wilkerson, L. Yan, C. L. Hodo, S. M. Kezar   +4 more
wiley   +1 more source

Quantitative and Phylogenetic Analyses of Immature Neurons in Cortical Layer II and Amygdala of Macaque Monkeys. [PDF]

Cells
Pattaro A, Ghibaudi M, Bramel M, Sherwood CC, Bonfanti L.   +4 more
europepmc   +1 more source

Scaling relationships between Haversian canal‐to‐secondary osteon and midshaft femur cortical‐to‐total area in a human autopsy sample

Journal of Anatomy, Volume 249, Issue 4, Page 865-882, October 2026.
We report that femoral cortical thickness was strongly and negatively associated with secondary osteon porosity in an Australian autopsy sample, indicating that thicker cortices contained less porous secondary osteons. This allometric relationship held for the whole sample, males and sedentary well‐nourished individuals, but not for females or other ...
Justyna J. Miszkiewicz, Laura A. B. Wilson, Karen M. Cooke, Rita Hardiman   +3 more
wiley   +1 more source

Proteomic Profiling of Cryopreservation-Induced Alterations in Rhesus Macaque Sperm. [PDF]

Andrology
Fan XJ, Fan XL, Zhang HT, Zhang JW, Liu YH, Zhuang XD, Chen L, Wang XR, Wei YL.   +8 more
europepmc   +1 more source