Results 61 to 70 of about 56,299 (265)

Strategies for inducing diabetes in laboratory animals: Advances from chemical, surgical, immunologic, dietary, and genetic approaches

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This review summarizes the principal experimental approaches used to induce diabetes in animal models. Strategies include chemical agents (streptozotocin, alloxan, dithizone, gold thioglucose), dietary interventions (high‐fat and high‐sugar diets), surgical methods (total or partial pancreatectomy), genetic models (db/db, ob/ob, Goto‐Kakizaki [GK ...
Milad Faraji   +2 more
wiley   +1 more source

Pyramidal cell development: postnatal spinogenesis, dendritic growth, axon growth, and electrophysiology.

open access: yesFrontiers in Neuroanatomy, 2014
Here we review recent findings related to postnatal spinogenesis, dendritic and axon growth, pruning and electrophysiology of neocortical pyramidal cells in the developing primate brain.
Guy eElston, Ichiro eFujita
doaj   +1 more source

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

open access: yesAngewandte Chemie International Edition, EarlyView.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber   +4 more
wiley   +1 more source

The role of the striatum in social behaviour

open access: yesFrontiers in Neuroscience, 2013
Where and how does the brain code reward during social behaviour? Almost all elements of the brain’s reward circuit are modulated during social behaviour. The striatum in particular is activated by rewards in social situations.
Raymundo eBáez-Mendoza   +1 more
doaj   +1 more source

The morphology of the oval window in Paranthropus robustus compared to humans and other modern primates

open access: yesThe Anatomical Record, EarlyView.
Abstract The oval window (OW) is an opening connecting the inner and middle ear. Its area has been shown to consistently scale with body mass (BM) in primates, and has been used alongside semi‐circular canal (SCC) size to differentiate Homo sapiens and fossil hominins, including Paranthropus robustus.
Ruy Fernandez, José Braga
wiley   +1 more source

Hepatic and pulmonary macrophage activity in a mucosal challenge model of Ebola virus disease

open access: yesFrontiers in Immunology
BackgroundThe inflammatory macrophage response contributes to severe Ebola virus disease, with liver and lung injury in humans.ObjectiveWe sought to further define the activation status of hepatic and pulmonary macrophage populations in Ebola virus ...
Timothy G. Wanninger   +7 more
doaj   +1 more source

Multi‐method analysis for the three‐dimensional reconstruction of muscle fascicles from DiceCT datasets

open access: yesThe Anatomical Record, EarlyView.
Abstract Muscle architecture is a major determinant of muscle performance and, in mammalian lineages, has been correlated with both feeding ecology and locomotor behaviors. Over the past decade, contrast‐enhanced micro‐CT (DiceCT) has emerged as an alternative to traditional dissection‐based measurement.
Aleksandra Ratkiewicz   +5 more
wiley   +1 more source

Patterns of interspecific variation in labial microarchitecture among anthropoid primates and the evolution of the hominin lips

open access: yesThe Anatomical Record, EarlyView.
Comparative histological and semi‐automated image analysis of primate lips: Masson's trichrome‐stained sagittal sections were segmented to quantify the connective tissue, adipose, and muscular components, enabling interspecific comparisons of labial architecture.
Liat Rotenstreich   +5 more
wiley   +1 more source

Descriptive, comparative, and functional anatomy of the facial musculature in cattle (Bos taurus)

open access: yesThe Anatomical Record, EarlyView.
Abstract Facial expressions can provide insight into animal emotions and pain, but no standardized system for assessing the entire facial display in cattle (Bos taurus Linnaeus) exists. The Facial Action Coding System (FACS), originally developed for humans, identifies distinct facial movements based on mimetic muscles.
Maja Söderlind   +6 more
wiley   +1 more source

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