Results 41 to 50 of about 79,205 (258)

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Male consort behavior is driven by female mate choice and receptive synchrony in Tibetan macaques (Macaca thibetana)

Global Ecology and Conservation
In group-living animals, males’ fighting abilities were usually mediated via dominance rank to sort males into a queue to access fertile females, especially in non-human primates. However, the correlation between male reproductive success and consortship,
Qi-Xin Zhang, Yong Zhu, Dong-Po Xia, Xi Wang, Jin-Hua Li   +4 more
doaj   +1 more source

Evaluation in Nonhuman Primates of Vaccines against Ebola Virus

Emerging Infectious Diseases, 2002
Ebola virus (EBOV) causes acute hemorrhagic fever that is fatal in up to 90% of cases in both humans and nonhuman primates. No vaccines or treatments are available for human use.
Thomas W. Geisbert, Peter Pushko, Kevin Anderson, Jonathan Smith, Kelly J. Davis, Peter B. Jahrling   +5 more
doaj   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Collective decision-making in nocturnal huddling sleep: The influence of social factors on fans and fandom in Tibetan macaques

Global Ecology and Conservation
Social animals frequently exhibit huddling sleep behaviors in response to nocturnal ecological pressures. However, there remain significant gaps in our understanding of the decision-making process promoting huddle sleep.
Juan Chen, Peipei Yang, Qixin Zhang, Wenbo Li, Xi Wang, Jinhua Li   +5 more
doaj   +1 more source

Translatability of Scalp EEG Recordings of Duration-Deviant Mismatch Negativity Between Macaques and Humans: A Pilot Study

Frontiers in Psychiatry, 2020
Mismatch negativity (MMN) is a negative deflection of the auditory event-related potential (ERP) elicited by an abrupt change in a sound presented repeatedly.
Mariko Tada, Mariko Tada, Yuki Suda, Yuki Suda, Kenji Kirihara, Daisuke Koshiyama, Mao Fujioka, Kaori Usui, Tsuyoshi Araki, Kiyoto Kasai, Kiyoto Kasai, Takanori Uka, Takanori Uka   +12 more
doaj   +1 more source

Surveillance of Daughter Micronodule Formation Is a Key Factor for Vaccine Evaluation Using Experimental Infection Models of Tuberculosis in Macaques

Pathogens, 2023
Tuberculosis (TB) is still a major worldwide health problem and models using non-human primates (NHP) provide the most relevant approach for vaccine testing.
Isabel Nogueira, Martí Català, Andrew D. White, Sally A Sharpe, Jordi Bechini, Clara Prats, Cristina Vilaplana, Pere-Joan Cardona   +7 more
doaj   +1 more source

“Monkey influencers”: conservation culturomics of human-macaque (Macaca fascicularis) interactions

Global Ecology and Conservation
Conservation culturomics can offer insights into the online presence of threatened primate species, such as the long-tailed macaque (Macaca fascicularis).
Alice Fratesi, Enrico Di Minin, Elodie F. Briefer, Daniel R.K. Nielsen   +3 more
doaj   +1 more source

Contextual factors explain risk-seeking preferences in rhesus monkeys

Frontiers in Neuroscience, 2013
In contrast to humans and most other animals, rhesus macaques strongly prefer risky rewards to safe ones with similar expected value. Why macaques prefer risk while other animals typically avoid it remains puzzling and challenges the idea that monkeys ...
Sarah eHeilbronner, Benjamin eHayden
doaj   +1 more source

Stimulus Feature-Specific Information Flow Along the Columnar Cortical Microcircuit Revealed by Multivariate Laminar Spiking Analysis

Frontiers in Systems Neuroscience, 2020
Most of the mammalian neocortex is comprised of a highly similar anatomical structure, consisting of a granular cell layer between superficial and deep layers. Even so, different cortical areas process different information. Taken together, this suggests
David A. Tovar, David A. Tovar, Jacob A. Westerberg, Jacob A. Westerberg, Jacob A. Westerberg, Michele A. Cox, Kacie Dougherty, Thomas A. Carlson, Mark T. Wallace, Mark T. Wallace, Mark T. Wallace, Mark T. Wallace, Mark T. Wallace, Mark T. Wallace, Mark T. Wallace, Alexander Maier, Alexander Maier, Alexander Maier   +17 more
doaj   +1 more source