Results 31 to 40 of about 28,400 (245)

Mitigating Cancer Therapy–Related Cognitive Impairment by Targeted Activation of Undruggable Phosphatase

Advanced Science, EarlyView.
An RVG‑engineered exosomal saRNA delivery system (RVG‑EVs‑saPtpro) effectively targets and activates hippocampal PTPRO, functioning as a “molecular brake” to alleviate cancer therapy‑related cognitive impairment (CTRCI) by enhancing neuronal survival, neurogenesis, and synaptic plasticity.
Zhimeng Yao, Yuhua Meng, Huanyi Li, Yinhui Jiang, Xiaona Lin, Mengyuan Hu, Qing Liu, Xiaofu Qiu, Hongzheng Ren, Yunlong Pan, Bin Pan, Zexiong Guo, Shuyao Zhang, Dianzheng Zhang, Li Yang, Shegan Gao, Weijing Deng, Jianfan Chen, Hao Zhang   +18 more
wiley   +1 more source

Legal Approaches and Regulatory Methods for Fintech in the Guangdong – Hong Kong – Macao Greater Bay Area

Journal of Digital Technologies and Law
Objective: To look at the fintech regulatory policy and regulatory system in the Greater Bay Area through the lens of the Trilemma of Innovation doctrine in order to identify the applicability and extrapolation of existing legal models in the zone of ...
Y. Kuchina
doaj   +1 more source

Unveiling Lactylation: A Novel Frontier in Cancer Stemness and Therapy

Advanced Science, EarlyView.
Tumor metabolism and epigenetic regulation are intrinsically linked. This review highlights lactylation as a pivotal bridge connecting these processes, acting as an active epigenetic effector in cancer stemness. We delineate how lactylation orchestrates the cancer stem cell landscape and evaluate its regulatory networks.
Ting Li, Hongyu Gu, Chang Liu, Yuesheng Lv, Feifei Li, Liang Liang, Jia Yi, Xuanyi Wang, Yi Zhun Zhu, Chuan Xu   +9 more
wiley   +1 more source

Planning Strategies for Increasing the Occupancy Rate of Green Open Space Based on Urban Geographic Data in Macau: An Investigation of Ultra-High-Density Cities

Buildings
Urban green space can effectively optimize the urban landscape and environment and provide residents with space for daily leisure and recreational activities.
Jitai Li, Fan Lin, Hongcan Cui, Yile Chen, Shuai Yang   +4 more
doaj   +1 more source

Structural features of the streetscape of Macau across four different spatial scales based on historical maps.

PLoS ONE, 2021
In the analysis of complex historical layering, studies on how to avoid theoretical analysis and use quantitative methods of display and analysis are scarce. Therefore, we used space syntax to fill this gap in historical layering analysis. We established
Youping Teng, Shuai Yang, Yue Huang
doaj   +1 more source

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

Advanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen, Yan Yang, Haihan Gao, Yan Liu, Xinyue Wang, Linghao Song, Ruohong Li, Ao Miao, Jie Xu, Zhennan Zhao, Dan Li, Shenjie Peng, Linzhao Li, Min Zhang, Yonghang Liu, Liren Wang, Tianhui Chen, Yongxiang Jiang   +17 more
wiley   +1 more source

Spatio-temporal patterns of the construction and development of urban open spaces in Macau from 1889–2020

Journal of Asian Architecture and Building Engineering
This study investigates the spatiotemporal evolution of urban open spaces in Macau from 1889 to 2020, aiming to uncover the historical progression of Macau’s urban landscape.
Jitai Li, Fan Lin, Yile Chen
doaj   +1 more source

Quantum Photothermal Self‐Monitoring Fiber Probes for In Vivo Photothermal Therapy

Advanced Science, EarlyView.
A miniaturized quantum photothermal fiber probe based on a metal/polymer/glass composite optoelectronic fiber that simultaneously guides lightwave and microwave was developed for the first time. The probe achieves enhanced photothermal conversion (13°C/mW, 25°C–120°C range) while providing real‐time self‐monitoring with 0.2°C thermal resolution at the ...
Wanjun Li, Ruixiao Hu, Jie Mao, Jin Wo, Yunsong Zhang, Liang Chen, Ying Liu, Zhibo Li, Yongxin Lin, Minghui Du, Yaofei Chen, Libing Zhou, Tuan Guo   +12 more
wiley   +1 more source

MACAU, CHINA: STATUS INTERNACIONAL ESPECIAL E DIREITOS FUNDAMENTAIS

Inter, 2019
Este artigo aborda o desenvolvimento do quadro político e da realidade jurídica de Macau, a partir de um sistema colonial para um não colonial por meio de uma transição política e constitucional pacífica.
Denis De Castro Halis
doaj  

Exploring the influence of audiences’ subjective well-being in sport event: the moderating role of leisure engagement

Tourism & Management Studies, 2020
Drawing on leisure coping theory, this study examines how negative impacts of sport events influence audiences’ subjective well-being, which further affects the support of the event. Leisure engagement is further employed to test its moderating effect of
Juan Tang , Jiayu Wu , Ben Kok Goh
doaj   +1 more source