Results 41 to 50 of about 10,886 (195)

PAISAGENS DE MACAU (SÉCS. XVIII-XIX) “VUE DE MACAO EN CHINE” VERSUS “ON THE GREEN”

open access: yesArt is on, 2015
O Museu do Centro Científico e Cultural de Macau (CCCM) conserva no seu acervo uma gravura e um desenho com vistas da cidade de Macau, dos finais do séc. XVIII e da primeira metade do séc. XIX.
Alexandrina Martins da Costa
doaj  

Structural features of the streetscape of Macau across four different spatial scales based on historical maps.

open access: yesPLoS ONE, 2021
In the analysis of complex historical layering, studies on how to avoid theoretical analysis and use quantitative methods of display and analysis are scarce. Therefore, we used space syntax to fill this gap in historical layering analysis. We established
Youping Teng, Shuai Yang, Yue Huang
doaj   +1 more source

Chemoselective Metabolomics via a Modular Reactivity‐Encoding Platform

open access: yesAdvanced Science, EarlyView.
Conventional LC–MS underrepresents numerous metabolites due to heterogeneous ionization efficiencies and matrix interference. Here, we introduce a modular reactivity‐encoding platform (MREP) comprising four alkyne‐tagged probes that selectively derivatize key functional groups, followed by unified click‐chemistry capture to eliminate matrix components ...
Xin Tao   +10 more
wiley   +1 more source

Reviewing the Fourth Plenum: Governance and Morality in the Era of Xi Jinping [PDF]

open access: yesContemporary Chinese Political Economy and Strategic Relations: An International Journal, 2019
Plenums are an opportunity for the Central Committee members to meet, and, of course, discuss a number of important issues pertaining to the state of the domestic economy, but also to national governance.
Alex Payette
doaj  

From Displacement to Angle: Diamond‐Based 3D Rotation Sensing for High‐Precision Cellular Force Measurement

open access: yesAdvanced Science, EarlyView.
Cellular forces are traditionally inferred from displacement measurements, which lack rotational information and are constrained by linear model assumptions. This work replaces displacement with rotational angle for the fundamental mechanical readout.
Linjie Ma   +8 more
wiley   +1 more source

Engineering‐Modulated Molybdenum Enzymes Strategy for Tumor‐Specific Metabolic‐Immunotherapy

open access: yesAdvanced Science, EarlyView.
Biodegradable molybdenum sulfide nanoparticles were synthesized via a one‐pot strategy to increase molybdenum enzyme activity and thus effectively potentiate anti‐tumor immunity by integrating molybdenum‐based metalloimmunotherapy with hydrogen sulfide gas therapy.
Xiaoxiao Pan   +14 more
wiley   +1 more source

Distribution characteristics and formation of religious spaces in Macau: an analysis based on points of interest (POIs) and social organization locations

open access: yesJournal of Asian Architecture and Building Engineering
Tangible religious sites shrink amid rapid urbanization in Macau. Religious buildings and institutions are integrated into a unified framework for analyzing their spatial distribution, clustering characteristics, and formative mechanisms.
Yufei Zhu   +7 more
doaj   +1 more source

Islands of China and the Sinophone world

open access: yesIsland Studies Journal, 2017
This special thematic section lays the groundwork for the development of island studies in the Sinophone world as well as introduces international scholars to the region’s islands. Papers are included from mainland China, Taiwan, Hong Kong, and Macau.
Adam Grydehøj, Otto Heim, Huan Zhang
doaj   +1 more source

Trafficking Deficiency of TMEM175 Variants in Parkinson's Disease Pathogenesis and the Prospects of Precision Medicine

open access: yesAdvanced Science, EarlyView.
This study identifies that the PD‐associated TMEM175‐L156P variant disrupts lysosomal ion channel trafficking by causing aberrant endoplasmic reticulum retention. A “chaperone–agonist” bifunctional small molecule restores TMEM175‐L156P lysosomal localization and channel function, thereby alleviating PD‐relevant cellular phenotypes and highlighting a ...
Ting Luo   +17 more
wiley   +1 more source

Ahcy Acts as an Effector of Hnf4a‐Driven Super‐Enhancer Activation to Alleviate MASLD During Intermittent Fasting

open access: yesAdvanced Science, EarlyView.
Our study identifies an Hnf4a‐driven super‐enhancer of hepatic Ahcy that mediates the protective effects of intermittent fasting against MASLD. Disruption of the Ahcy super‐enhancer reduces Ahcy expression and exacerbates lipid accumulation. This pathway prevents aberrant promoter hypermethylation by maintaining the SAM/SAH balance, as exemplified by ...
Huafeng Chen   +6 more
wiley   +1 more source

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