Progress in Muon Cooling Research and Development
The MuCool R&D program is described. The aim of MuCool is to develop all key pieces of hardware required for ionization cooling of a muon beam. This effort will lead to a more detailed understanding of the construction and operating costs of such ...
Kaplan, Daniel M.
core +3 more sources
Rain water harvesting management system in Zoo Negara, Selangor [PDF]
Water is a key requirement either to human, animal or plant. Rainwater Harvesting System (RWH) is a technology used to collect and store rainwater from the roof for reuse.
Md Yassin, Azlina +3 more
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Dry sliding friction and wear response of WC-Co hardmetal pairs in linearly reciprocating and rotating contact [PDF]
This paper presents an experimental evaluation of friction and wear properties of WC-Co cemented carbides. A comparison is made between unlubricated rotating and linearly reciprocating pin-onplate sliding pairs. The plate specimens were WC-10wt%Co grades
Bonny, Koenraad +7 more
core +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Effect of Reinforcement Content and Cutting Parameters on Tool Wear in Machining of Aluminum Hybrid Composites [PDF]
The machinability of aluminum hybrid composites (AHCs) can be enhanced by utilization of optimum composition and cutting parameters. In this study, the machinability of AHCs containing micron-sized TiB2 and B4C particles was investigated using the face ...
I. Sarpkaya +4 more
doaj +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Machinability testing for gear hobbing applications [PDF]
ArcelorMittal focuses on both mechanical performances and machinability while designing new steel grades. ArcelorMittal has developed specific programs for machinability testing in turning, low and high speed drilling and gear machining. Machinability is
BOMONT, Olivier +3 more
core +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
The machinability of nickel-based alloys in high-pressure jet assisted (HPJA) turning
Due to their mechanical, thermal and chemical properties, nickel-based alloys are generally included among materials that are hard to machine. An experimental study has been performed to investigate the capabilities of conventional and high-pressure jet ...
D. Kramar +3 more
doaj

