Results 51 to 60 of about 1,135,266 (267)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
The Machine in the Text, and the Text in the Machine
Digital Humanities Quarterly, 2010 The Machine in the Text, and the Text in the Machine is a review essay on Electronic Literature: New Horizons for the Literary (Notre Dame, IN: University of Notre Dame, 2008), by N. Katherine Hayles, and Mechanisms: New Media and the Forensic Imagination (Cambridge, Mass.: MIT Press, 2008), by Matthew G. Kirschenbaum.
openaire +3 more sources
The Machine and the Camp: The Projectuality of the Holiday Spaces in the Third Reich
In_BoThis paper aims to analyse the ambiguous relationship with modernity of the holiday spaces in the Third Reich. The Kraft durch Freude (KdF) and the Hitlerjugend, the two major Nazi organisations dedicated to normalising the leisure time of the Reich's ...
Gianluca Drigo
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Engineering ProceedingsThis paper describes the creativity, design, and construction of a customized sago machine with a kneading pipe, filter, storage tank, and shredder. The main objective of this innovation is to maximize the conversion of sago stems into superior starch ...
Iniovaine Lekakali +4 more
doaj +1 more source
Revista Brasileira de Engenharia Agrícola e Ambiental, 2006 Os métodos de trilhamento das plantas não proporcionam grãos limpos, em condições de serem comercializados, semeados ou armazenados. É necessário que passem por um processo de limpeza com o fim de eliminar os fragmentos dos próprios grãos, detritos ...
José G. da Silva, Dino M. Soares
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Transactions of the VŠB-Technical University of Ostrava, Mechanical Series, 2011 Difficult operating conditions at mining put high demands on technical responsibility of mechanical machines and influence the operator of mechanical machines in a negative way as well.
Jan BLATA +3 more
doaj +1 more source