Results 81 to 90 of about 6,500,691 (338)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Evaluation of Hindi to Punjabi Machine Translation System [PDF]
, 2009 Machine Translation in India is relatively young. The earliest efforts date from the late 80s and early 90s. The success of every system is judged from its evaluation experimental results.
Goyal, Vishal, SINGH LEHAL, Gurpreet
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Advances in Electrical and Electronic Engineering, 2006 This research has been motivated by industrial demand for single phase current-source active rectifier dedicated for reconstruction of older types of dc machine locomotives. This paper presents converters control structure design and simulations.
Jan Michalik +2 more
doaj
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
EXTENDED TECHNICAL INSPECTION FOR PATH OF ROLLING FROM M5A COAL REMOVAL MACHINE [PDF]
Journal of Research and Innovation for Sustainable Society, 2020 This path of rolling is carried out on longitudinal ties of reinforced concrete and is formed from the superstructure 49 by 15 m length, fixed to the metal plates 49 with the clamping indirect type.The way of rolling has 680 m of which is operated on a
Alin STĂNCIOIU
doaj
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Individual Explanations in Machine Learning Models: A Case Study on Poverty Estimation [PDF]
, 2021 Alfredo Carrillo +3 more
openalex +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Metaphysical Primitives: Machines and Assemblages in Deleuze, DeLanda, and Bryant
Open Philosophy, 2020 Some variants of Object-Oriented Ontology define entities in terms of their powers. Such variants are rooted in Gilles Deleuze and Félix Guattari’s theory of “machinic assemblages”.
Kleinherenbrink Arjen
doaj +1 more source