Results 21 to 30 of about 3,579,627 (239)

Thermal Analysis for Condition Monitoring of Machine Tool Spindles [PDF]

open access: yes, 2012
Decreasing tolerances on parts manufactured, or inspected, on machine tools increases the requirement to have a greater understanding of machine tool capabilities, error sources and factors affecting asset availability. Continuous usage of a machine tool
Willoughby, P.   +7 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Evaluation and Comparison of a Large Machine Tool Structure with ISO Standard Alignment Tests [PDF]

open access: yes, 2009
In order to satisfactorily machine precision components it is necessary for machine tools to be able to achieve extremely high levels of geometric accuracy.
Longstaff, Andrew P.   +4 more
core   +5 more sources

Sidney Machine Tool Company lathe photograph

open access: yes
This photograph shows a lathe at the Sidney Machine Tool Company. Sidney Tool Company was founded in 1905 by Alfred C. Getz in Sidney, Ohio. Getz was also acting plant manager for Monarch Machine Tool, also in Sidney, during the same time.
Sidney Machine Tool Company
core   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Torque ripple reduction of a direct-drive permanent-magnet synchronous machine by material-efficient axial pole pairing [PDF]

open access: yes, 2011
This paper investigates a material-efficient axial pole pairing method for torque ripple reduction in a direct-drive outer-rotor surface-mounted permanent-magnet synchronous machine.
Patrick Chi-Kwong Luk   +3 more
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Influence of Rotor Structure and Number of Phases on First and Second Order Characteristics of TOYOTA PRIUS Electrical Machine Type [PDF]

open access: yes, 2011
Version enrichie dans Journal of Energy and Power Engineering-2012.09 pp1461 a 1471This paper investigates the influence of the rotor structure on torque and Flux weakening region of V-shape IPM machine from TOYOTA PRIUS type, more specifically ...
VIGIER, Thimoté   +3 more
core  

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