Results 71 to 80 of about 7,806,329 (300)

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Targeted Active Learning for Bayesian Decision-Making

Active learning is usually applied to acquire labels of informative data points in supervised learning, to maximize accuracy in a sample-efficient way.
Kaski, Samuel, Tiulpin, Aleksei, Filstroff, Louis, Sundin, Iiris, Kylmäoja, Juuso, Mikkola, Petrus   +5 more
core   +1 more source

Spatially resolved rainfall streamflow modeling in central Europe [PDF]

Hydrology and Earth System Sciences
Climate change increases the risk of disastrous floods and makes intelligent freshwater management an ever more important issue for society. A central prerequisite is the ability to accurately predict the water level in rivers from a range of predictors,
M. A. Vischer, N. Otero, J. Ma
doaj   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

A Probabilistic Adversarial Autoencoder for Novelty Detection: Leveraging Lightweight Design and Reconstruction Loss

IEEE Access
A novelty detection task involves identifying whether a data point is an outlier, given a training dataset that primarily captures the distribution of inliers. The novel class is usually absent, poorly sampled, or not well defined in the training data. A
Muhammad Asad, Ihsan Ullah, Muhammad Adeel Hafeez, Ganesh Sistu, Michael G. Madden   +4 more
doaj   +1 more source

Spatially resolved meteorological and ancillary data in Central Europe for rainfall streamflow modeling [PDF]

Earth System Science Data
We present a gridded dataset for rainfall streamflow modeling that is fully spatially resolved and covers five complete river basins in central Europe: upper Danube, Elbe, Oder, Rhine, and Weser (https://doi.org/10.4211/hs ...
M. A. Vischer, N. Otero, J. Ma
doaj   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi, Giorgio Ricciardiello Mejia, Andre Metzger, Kang Hyun Ryu, Salonee Marwaha, Eva Grzegorczyk, Li Zhou, Eliana Jacobs, Boris Gilyadov, Claudia Kunney, Liqhwa Ncube, Ankit Parekh, Emmanuel Mignot, Fanny M. Elahi, Joseph Winer, Kathleen Poston, Andreas Brink‐Kjaer, Emmanuel H. During   +17 more
wiley   +1 more source

Intelligent pavement management: a machine learning framework for condition classification and maintenance prioritization

Scientific Reports
Efficient pavement maintenance requires reliable classification of pavement condition and clear prioritization of interventions. This study develops and benchmarks a multi-model machine learning framework for pavement condition classification in both ...
Bhoomika Gupta, Mannya Agrawal, Preeti Narooka, Deepak Panwar, Sanchit Anand   +4 more
doaj   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

The Natural Language Decathlon: Multitask Learning as Question Answering

, 2018
Presented on August 28, 2018 at 12:15 p.m. in the Pettit Microelectronics Research Center, Room 102 A/B.Bryan McCann is a Senior Research Scientist at Salesforce.
McCann, Bryan
core   +1 more source