Results 111 to 120 of about 3,032,047 (392)
Glucocorticoids Alter Bone Microvascular Barrier via MAPK/Connexin43 Mechanisms
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.Osteoporosis induced by Glucocorticoids (GCs) is a common complication of long‐term GC use in patients with inflammatory and autoimmune conditions, often leading to an increased fracture risk. A 3D bicellular endo‐osteo microfluidic platform is developed to explore pathogenic mechanisms underlying GCs‐induced osteoporosis, highlighting a novel MAPK ...
Eun‐Jin Lee +10 more
wiley +1 more source
Unsupervised learning for vascular heterogeneity assessment of glioblastoma based on magnetic resonance imaging: The Hemodynamic Tissue Signature [PDF]
arXiv, 2020 This thesis focuses on the research and development of the Hemodynamic Tissue Signature (HTS) method: an unsupervised machine learning approach to describe the vascular heterogeneity of glioblastomas by means of perfusion MRI analysis. The HTS builds on the concept of habitats.
arxiv
Journal of Clinical Medicine, 2022 Background: The gap between the demand and supply of donor livers is still a considerable challenge. Since static cold storage is not sufficient in marginal livers, machine perfusion is being explored as an alternative. The objective of this study was to
Joseph Mugaanyi +5 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.A wireless cortical surface implant employing graphene electrode arrays diagnoses and alleviates Parkinson's disease symptoms in freely moving animals. The device continuously monitors cortical activity and delivers targeted stimulation, restoring beta–gamma and delta oscillations.
Hongseong Shin +15 more
wiley +1 more source
UniToBrain dataset: a Brain Perfusion Dataset [PDF]
arXiv, 2022 The CT perfusion (CTP) is a medical exam for measuring the passage of a bolus of contrast solution through the brain on a pixel-by-pixel basis. The objective is to draw "perfusion maps" (namely cerebral blood volume, cerebral blood flow and time to peak) very rapidly for ischemic lesions, and to be able to distinguish between core and penumubra regions.
arxiv
Predicting Early Allograft Function After Normothermic Machine Perfusion
Transplantation, 2022 Background. Normothermic ex situ liver perfusion is increasingly used to assess donor livers, but there remains a paucity of evidence regarding criteria upon which to base a viability assessment or criteria predicting early allograft function.
C. Watson +11 more
semanticscholar +1 more source
Hypothermic Machine Perfusion Preservation of the DCD Kidney: Machine Effects [PDF]
Journal of Transplantation, 2013 Purpose. Kidneys from DCD donors represent a significant pool, but preservation problems exist. The study objective was to test the importance of machine type for hypothermic preservation of DCD kidneys.Methods. Adult Beagle dog kidneys underwent 45 minutes of warm in situ ischemia followed by hypothermic perfusion for 24 hours (Belzer-MPS Solution) on
Lindell, Susanne L. +3 more
openaire +5 more sources
Pulsatile preservation in kidney transplantation: strengths, limitations and future directions. [PDF]
, 2019 [EN] Systematic review on hypothermic machine perfusion in kidney transplantation storage versus actual storage in cold ischemia. The introduction also includes basics on kidney transplantation and overview of hypothermic machine perfusion and storage ...
Rojo Ruiz, Nagore
core
Transplantation of high risk donor livers:Machine perfusion studies to improve and predict post transplant hepatobiliary function [PDF]
, 2020 There currently is a shortage of suitable donor livers in the Netherlands. In 2016, waiting list mortality was 17%. In that same year 32% of all donor livers were declined for transplantation, due to an estimated high risk of complications, such as ...
de Vries, Yvonne
core +2 more sources
Advanced Healthcare Materials, EarlyView.Clinical translation of biohybrid medical implants requires the previous implementation of drying schemes that can facilitate their sterilization and storage. This study addresses that critical aspect and elucidates the impact of drying on biohybrid vascular grafts, highlighting the need for implant‐specific drying strategies to ensure safety ...
Dominic Pascal Andre +5 more
wiley +1 more source