Results 231 to 240 of about 2,924,807 (328)

A Review on Quantitative Process Analytical Technology for Continuous Downstream Processing of Monoclonal Antibodies

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The competition in the biopharmaceutical market is increasing due to the market entry of biosimilars and rising costs in research and development of new drugs. Hence, continuous manufacturing gained significant attention due to its potential in reducing production cycle times and costs, as well as the possibility of real‐time release testing ...
Mariana Carvalho, Ana Cruz, Cees Haringa, Marcel Ottens, Marieke Klijn   +4 more
wiley   +1 more source

Opportunities and challenges with the implementation of normothermic machine perfusion in kidney transplantation. [PDF]

Nat Commun
Rabelink TJ, Hosgood S, Minor T, Selzner M, Weissenbacher A, Leuvenink HG, Schneeberger S.   +6 more
europepmc   +1 more source

The Use of Normothermic Machine Perfusion for Staged Combined Heart-Liver Transplant. [PDF]

Case Rep Transplant
Kwon YIC, Khan A, Bruno DA, Hashmi ZA, Chery J.   +4 more
europepmc   +1 more source

Renal Arterial Anatomy: Implications for Normothermic Machine Perfusion in Renal Transplantation

Clinical Anatomy, EarlyView.
ABSTRACT Normothermic machine perfusion (NMP) is a novel technology that has shown potential in viability assessment and reconditioning of donor organs. Normothermic machine perfusion is technically more challenging in kidneys with multiple renal arteries (RAs).
Lily Mae Miller, Peter Douglas, Julie Glen, Emma Aitken   +3 more
wiley   +1 more source

Spectral Analysis of Extrahepatic Bile Ducts During Normothermic Liver Machine Perfusion. [PDF]

Bioengineering (Basel)
Zelger P, Jenewein B, Sovago M, Krendl FJ, Meszaros AT, Cardini B, Gehwolf P, Pallua JD, Graf S, Schneeberger S, Fodor M, Oberhuber R.   +11 more
europepmc   +1 more source

Fractal Anatomy of Human Organs: A Narrative Review of Structure, Function, and Clinical Perspectives

Clinical Anatomy, EarlyView.
ABSTRACT Fractal geometry describes complex, self‐similar patterns that repeat across spatial scales and is increasingly recognized as relevant in anatomical research. Indeed, the fractal organization is consistently observed in respiratory, cardiovascular, gastrointestinal, nervous, renal, hepatic, and dermatological systems.
Immacolata Belviso, Jacopo Junio Valerio Branca, Giulia Guarnieri, Annamaria Morelli, Alessandra Pacini, Daniele Della Posta, Domenico Ribatti, Ferdinando Paternostro   +7 more
wiley   +1 more source

Cardiovascular‐Kidney‐Metabolic Syndrome in People With HIV: An Emerging Frontier for Clinical Pharmacology

Clinical Pharmacology &Therapeutics, EarlyView.
As antiretroviral therapy (ART) prolongs lifespans, people with HIV (PWH) face a new syndemic: Cardiovascular‐Kidney‐Metabolic (CKM) syndrome. Yet CKM in PWH is poorly characterized. Inflammation, complex pharmacokinetic (PK) alterations, ART‐associated metabolic effects, and gut dysbiosis amplify risk. Managing CKM increases medication burden, thereby
Aaron S. Devanathan, Thomas D. Nolin
wiley   +1 more source

Is 2 h of Hypothermic Machine Perfusion for Pancreas Preservation Effective in Improving Graft Reperfusion? [PDF]

Transplant Direct
Mesnard B, Masset C, Ogbemudia E, Bruneau S, Elzawahry M, Le Bas-Bernardet S, Minault D, Hervouet J, Cantarovich D, Rigaud J, Badet L, Friend P, Ploeg R, Blancho G, Hunter J, Prudhomme T, Branchereau J.   +16 more
europepmc   +1 more source

Constructing a model of the blood flow in the human liver using contrast-loaded corrosion casting and micro-CT imaging [PDF]

, 2009
Casteleyn, Christophe, Cornillie, Pieter, Debbaut, Charlotte, Masschaele, Bert, Monbaliu, Diethard, Pirenne, Jacques, Segers, Patrick, Simoens, Paul, Van Hoorebeke, Luc, Van Loo, Denis   +9 more
core   +1 more source

Dynamic expression of lamin B1 during adult neurogenesis in the vertebrate brain

Developmental Dynamics, EarlyView.
Abstract Background In mammals, specific brain regions such as the dentate gyrus (DG) of the hippocampus and the subventricular zone (SVZ) of the lateral ventricles harbor adult neural stem/progenitor cells (ANSPCs) that give rise to new neurons and contribute to structural and functional brain plasticity.
Diana Zhilina, Lizbeth A. Bolaños Castro, Juan Sebastian Eguiguren, Sara Zocher, Anne Karasinsky, Dimitri Widmer, Alexandre Espinós, Victor Borrell, Michael Brand, Kyoko Miura, Oliver Zierau, Maximina H. Yun, Tomohisa Toda   +12 more
wiley   +1 more source