Results 271 to 280 of about 2,924,807 (328)

Reshaping study design for faster extrapolation‐based drug approval in pediatric inflammatory bowel diseases: An ESPGHAN–NASPGHAN position paper

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Children with inflammatory bowel diseases (IBD) have limited access to the available advanced therapies, given the lengthy gap between adult and pediatric approval. We aimed to review key hurdles for pediatric trials and recommend practical solutions.
Dan Turner   +21 more
wiley   +1 more source

Nationwide Hypothermic Machine Perfusion for ECD and DCD Kidney Transplantation in Belgium: One-Year Outcomes and Impact on Transplant Rates and Budget Impact Analysis. [PDF]

open access: yesTranspl Int
Darius T   +15 more
europepmc   +1 more source

International Contrast Ultrasound Society Safety Round Table

open access: yesJournal of Ultrasound in Medicine, EarlyView.
The international Contract Ultrasound Society (ICUS) held a round table discussion on the safety of ultrasound contrast agents for cardiology, radiology, and pediatrics on September 4, 2024. The panel included international experts on ultrasound contrast.
Richard G. Barr   +5 more
wiley   +1 more source

Noninvasive <sup>13</sup>C-methacetin Liver Function Breath Test as a Tool for Functional Assessment During Normothermic Machine Perfusion of Porcine Livers. [PDF]

open access: yesTransplant Direct
Cammann S   +9 more
europepmc   +1 more source

Overview of Diagnostic Ultrasound Safety

open access: yesJournal of Ultrasound in Medicine, EarlyView.
Ultrasound is widely regarded as a safe imaging modality; however, emerging ultrasound‐based techniques—such as shear wave elastography and contrast‐enhanced ultrasound—operate with varying acoustic output parameters that may approach or exceed traditional diagnostic limits. As these technologies are increasingly integrated into human research studies,
Saubhagya Srivastava   +5 more
wiley   +1 more source

Fetal Ductal Constriction, Pulmonary Hypertension and Atrial Septum Mobility

open access: yesJournal of Ultrasound in Medicine, EarlyView.
Objectives Fetuses with ductal constriction (FDC), pulmonary hypertension and right ventricular overload after maternal exposure to PGE2 inhibitors—nonsteroidal anti‐inflammatory drugs (NSAIDs) or polyphenols (PF)—have increased septum primum excursion index (SPEI), the ratio between maximal septum primum displacement and left atrial diameter.
Paulo Zielinsky   +5 more
wiley   +1 more source

Survey of Early Practices and Perceptions of Liver Machine Perfusion Among US Liver Transplant Surgeons. [PDF]

open access: yesTransplant Direct
Nguyen MC   +8 more
europepmc   +1 more source

Rosuvastatin Upregulates RCOR1 to Repress C10ORF10 Transcription and Alleviate Oxidative Stress and Plaque Formation in Atherosclerosis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Rosuvastatin (RVS) is an HMG‐CoA reductase inhibitor with lipid‐lowering properties. This study aims to investigate the role of RVS in plaque formation in atherosclerosis (AS) and its functional mechanism. ApoE−/− mice were fed a high‐fat diet to generate a mouse model of AS.
Xin Fu   +5 more
wiley   +1 more source

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