Results 291 to 300 of about 2,924,807 (328)

Normothermic Machine Perfusion Systems: Where Do We Go From Here?

Transplantation, 2023
Normothermic machine perfusion (NMP) aims to preserve organs ex vivo by simulating physiological conditions such as body temperature. Recent advancements in NMP system design have prompted the development of clinically effective devices for liver, heart,
S. López-Martínez, C. Simón, X. Santamaria   +2 more
semanticscholar   +1 more source

Machine perfusion in kidney transplantation

Current Opinion in Organ Transplantation, 2019
Purpose of review The shortage of kidneys for transplantation has led to an urgent need to efficiently utilize the available cadaveric kidneys. Efficient use of machine perfusion may potentially lead to increased use of marginal kidneys by lowering the incidence of delayed graft function (DGF) and improving graft outcomes.
Ashish, Kataria, Sandeep, Magoon, Binni, Makkar, Aijaz, Gundroo   +3 more
openaire   +2 more sources

Normothermic Machine Perfusion for Declined Livers: A Strategy to Rescue Marginal Livers for Transplantation.

Journal of the American College of Surgeons, 2023
BACKGROUND Organ waste is a major cause of the donor liver shortage. Roughly 67% of recovered organ donors have liver utilization annually. A new technology called Normothermic Machine Perfusion (NMP) offers a way to recover marginal and declined livers ...
Franklin C. Olumba, F. Zhou, Yikyung Park, W. Chapman   +3 more
semanticscholar   +1 more source

Hypothermic machine perfusion for uterus transplantation

Fertility and Sterility, 2023
To describe the feasibility of hypothermic machine perfusion (HMP) in uterus transplantation (UT) to potentially improve the preservation of the uterus and enhance graft preservation in the donation after brainstem death (DBD) context. Uterus transplantation is a new surgical approach to treating absolute uterine infertility; it can be performed after ...
Ludivine Dion, Carla Sousa, Karim Boudjema, David Val-Laillet, Sylvie Jaillard, Nathalie Rioux-Leclercq, Erwan Flecher, Vincent Lavoue   +7 more
openaire   +2 more sources

Obstacles to implement machine perfusion technology in routine clinical practice of transplantation - Why are we not there yet ?

Hepatology, 2023
Machine perfusion of solid human organs is an old technique, and the basic principles were presented as early as in 1855 by Claude Barnard. More than 50years ago, the first perfusion system was used in clinical kidney transplantation.
Mauricio Flores Carvalho, Y. Boteon, J. Guarrera, P. Modi, L. Lladó, G. Lurje, M. Kasahara, P. Dutkowski, A. Schlegel   +8 more
semanticscholar   +1 more source

Liver transplantation with uncontrolled versus controlled DCD donors using normothermic regional perfusion and ex-situ machine perfusion

Liver transplantation, 2023
In Italy, 20 minutes of continuous, flat-line electrocardiogram are required for death declaration, which significantly increases the risks of donation after circulatory death (DCD) LT.
D. Ghinolfi, D. Patrono, R. De Carlis, F. Melandro, V. Buscemi, Francesca Farnesi, F. Torri, A. Lauterio, Maria Di Salvo, Raffaele Cerchione, Marinella Zanierato, R. Morganti, R. Romagnoli, P. De Simone, L. D. De Carlis   +14 more
semanticscholar   +1 more source

Improved Outcomes and Resource Use With Normothermic Machine Perfusion in Liver Transplantation.

JAMA Surgery
Importance Normothermic machine perfusion (NMP) has been shown to reduce peritransplant complications. Despite increasing NMP use in liver transplant (LT), there is a scarcity of real-world clinical experience data.
Michelle C. Nguyen, Chi Zhang, Yu-Hui Chang, Xingjie Li, Stephanie Y. Ohara, Kayla R Kumm, Christopher P Cosentino, B. Aqel, B. Lizaola-Mayo, Peter E. Frasco, R. Nunez-Nateras, W. Hewitt, Jack W Harbell, N. Katariya, A. Singer, Adyr A Moss, Kunam S. Reddy, Caroline C Jadlowiec, Amit K. Mathur   +18 more
semanticscholar   +1 more source

Myocardial perfusion characteristics during machine perfusion for heart transplantation

Surgery, 2008
Optimal parameters for machine perfusion preservation of hearts prior to transplantation have not been determined. We sought to define regional myocardial perfusion characteristics of a machine perfusion device over a range of conditions in a large animal model.Dog hearts were connected to a perfusion device (LifeCradle, Organ Transport Systems, Inc ...
Matthias, Peltz, Michael L, Cobert, David H, Rosenbaum, LaShondra M, West, Michael E, Jessen   +4 more
openaire   +2 more sources

Outcomes of DCD Liver Transplant Using Sequential Normothermic Regional Perfusion and Normothermic Machine Perfusion or NRP Alone Versus Static Cold Storage.

Transplantation
BACKGROUND The availability of in situ normothermic regional perfusion (NRP) or ex situ normothermic machine perfusion (NMP) has revolutionized donation after circulatory death (DCD) liver transplant (LT).
K. Croome, Vijay Subramanian, Amit K. Mathur, B. Aqel, Shennen A Mao, Jacob N. Clendenon, D. Perry, K. Dhanireddy, C. Taner   +8 more
semanticscholar   +1 more source

Sequential Normothermic Regional Perfusion and End-ischemic Ex Situ Machine Perfusion Allow the Safe Use of Very Old DCD Donors in Liver Transplantation

Transplantation
Background. In Italy, 20 min of continuous, flat-line electrocardiogram are required for death declaration. Despite prolonged warm ischemia time, Italian centers reported good outcomes in controlled donation after circulatory death (cDCD) liver ...
F. Torri, E. Balzano, Fabio Melandro, P. Maremmani, P. Bertini, Paolo Lo Pane, M. Masini, M. I. Rotondo, S. Babboni, S. Del Turco, Stefano Antonelli, V. De Tata, G. Biancofiore, F. Guarracino, Aldo Paolicchi, Paolo De Simone, G. Basta, D. Ghinolfi   +17 more
semanticscholar   +1 more source