Results 301 to 310 of about 2,924,807 (328)

Normothermic machine perfusion of the kidney

Current Opinion in Organ Transplantation, 2017
Normothermic machine perfusion (NMP) is a preservation method that is generating increasing interest. The aim of this review is to summarise the current status of NMP in regards of kidney viability assessment, reducing organ damage and improving transplant logistics.The results of recent large animal experiments and clinical trials show that continuous
Annemarie, Weissenbacher, James, Hunter
openaire   +2 more sources

Normothermic Machine Perfusion and Normothermic Regional Perfusion of DCD Kidneys Before Transplantation: A Systematic Review

Transplantation
Background. To overcome organ shortages, donation after circulatory death (DCD) kidneys are being increasingly used for transplantation. Prior research suggests that DCD kidneys have inferior outcomes compared with kidneys donated after brain death ...
Rowan Klein Nulend, Ahmer M Hameed, Animesh Singla, Lawrence Yuen, Taina Lee, Peter Yoon, Christopher B Nahm, Germaine Wong, Jerome Laurence, Wai H. Lim, Wayne J. Hawthorne, H. Pleass   +11 more
semanticscholar   +1 more source

Machine perfusion for cardiac allograft preservation

Current Opinion in Organ Transplantation, 2008
The current cardiac preservation strategy for cardiac transplantation involves arresting hearts with a crystalloid preservation solution and storing them in this solution in an ice chest. This technique has allowed good results in heart transplantation, but has limited the transport interval, and has not encouraged major efforts to expand the donor ...
Michael L, Cobert, LaShondra M, West, Michael E, Jessen   +2 more
openaire   +2 more sources

Hypothermic Oxygenated Machine Perfusion Reduces Early Allograft Injury and Improves Post-transplant Outcomes in Extended Criteria Donation Liver Transplantation From Donation After Brain Death

Annals of Surgery, 2021
Supplemental Digital Content is available in the text Objective: The aim of this study was to evaluate peak serum alanine aminotransferase (ALT) and postoperative clinical outcomes after hypothermic oxygenated machine perfusion (HOPE) versus static cold ...
Z. Czigany, J. Pratschke, J. Fronek, M. Guba, Wenzel Schöning, D. Raptis, J. Andrassy, M. Kramer, P. Strnad, R. Tolba, Wenjia Liu, T. Keller, Hannah Miller, Sandra Pavicevic, Deniz Uluk, M. Kocik, Isabella Lurje, C. Trautwein, A. Mehrabi, I. Popescu, F. Vondran, C. Ju, F. Tacke, U. Neumann, G. Lurje   +24 more
semanticscholar   +1 more source

Ex vivo kidney machine perfusion: meta-analysis of randomized clinical trials.

British Journal of Surgery
BACKGROUND Machine perfusion is an organ preservation strategy used to improve function over simple storage in a cold environment. This article presents an updated systematic review and meta-analysis of machine perfusion in deceased donor kidneys ...
Minseok Kang, Seonju Kim, Ji Yoon Choi, Kyeong Sik Kim, Yun Kyung Jung, Boyoung Park, Dongho Choi   +6 more
semanticscholar   +1 more source

Machine perfusion in liver transplantation: recent advances and coming challenges

Current Opinion in Organ Transplantation
Purpose of review Machine perfusion has been adopted into clinical practice in Europe since the mid-2010s and, more recently, in the United States (US) following approval of normothermic machine perfusion (NMP).
C. Wehrle, Chunbao Jiao, Keyue Sun, Mingyi Zhang, R. Fairchild, Charles Miller, Koji Hashimoto, A. Schlegel   +7 more
semanticscholar   +1 more source

Microbial Contamination During Long-term Ex Vivo Normothermic Machine Perfusion of Human Livers

Transplantation, 2023
Background. Normothermic machine perfusion permits the ex vivo preservation of human livers before transplantation. Long-term perfusion for days-to-weeks provides the opportunity for enhanced pretransplant assessment and potential regeneration of organs.
Ngee-Soon Lau, M. Ly, Claude Dennis, Shamus C. Toomath, Joanna Huang, Joanna Huang, H. Ly, S. Chanda, T. Marinelli, Rebecca J. Davis, Ken Liu, G. McCaughan, M. Crawford, C. Pulitano   +13 more
semanticscholar   +1 more source

Hypothermic machine perfusion in kidney transplantation

Current Opinion in Organ Transplantation, 2016
This article summarizes novel developments in hypothermic machine perfusion (HMP) as an organ preservation modality for kidneys recovered from deceased donors.HMP has undergone a renaissance in recent years. This renewed interest has arisen parallel to a shift in paradigms; not only optimal preservation of an often marginal quality graft is required ...
De Deken, Julie, Moers, Cyril, Kocabayoglu, Peri   +2 more
openaire   +2 more sources

Extracorporeal machine liver perfusion

Current Opinion in Organ Transplantation, 2012
Recently, considerable focus has been placed on the use of hypothermic perfusion ex vivo in abdominal organ transplant. Herein, we discuss the appropriateness of using this modality to preserve livers, in particular those of suboptimal quality, and whether perfusing at warmer temperatures in this context may, in fact, be better.Hypothermic perfusion (0-
Amelia J, Hessheimer, Constantino, Fondevila, Juan C, García-Valdecasas   +2 more
openaire   +2 more sources

Machine Perfusion of Organs

2017
Transplant organ supplies are insufficient to meet the demands, resulting in prolonged patient wait times and waitlist mortality. Offering improved organ preservation, assessment, and resuscitation, machine perfusion of organs can enable the use of marginal organs, thereby expanding the donor pool.
Matthew F. Blum, Qiang Liu, Basem Soliman, Toshihiro Okamoto, Bahar Bassiri-Gharb, Teresa Diago Uso, Laura D. Buccini, Cristiano Quintini   +7 more
openaire   +1 more source