Results 121 to 130 of about 3,637,202 (294)

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Digital Habits and Time Use Patterns: Factors Influencing Reading Comprehension Skills in Spanish Adolescents Based on PISA 2022

open access: yesHuman Behavior and Emerging Technologies
Adolescents’ reading comprehension skills are shaped by various activities and contextual factors. Identifying these determinants is imperative for improving academic performance.
Juan Ramón Rico-Juan   +2 more
doaj   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

open access: yesFEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao   +23 more
wiley   +1 more source

DRCD: a Chinese Machine Reading Comprehension Dataset

open access: yesCoRR, 2018
5 ...
Chih-Chieh Shao   +4 more
openaire   +2 more sources

A method of improving the performance of extractive reading comprehension model by using adversarial samples

open access: yes四川大学学报. 自然科学版
Extractive machine reading comprehension is a crucial task in natural language processing,where machines are required to extract the answer (fragments in inputting text) to a given question on the base of reading and understanding natural language text ...
HE Dong   +4 more
doaj  

Machine Reading Comprehension Model Based on Fusion of Mixed Attention

open access: yesApplied Sciences
To address the problems of the insufficient semantic fusion between text and questions and the lack of consideration of global semantic information encountered in machine reading comprehension models, we proposed a machine reading comprehension model ...
Yanfeng Wang, Ning Ma, Zechen Guo
doaj   +1 more source

VS3‐NET: Neural variational inference model for machine‐reading comprehension

open access: yesETRI Journal, 2019
We propose the VS3‐NET model to solve the task of question answering questions with machine‐reading comprehension that searches for an appropriate answer in a given context.
Cheoneum Park, Changki Lee, Heejun Song
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Answering the questions of “which, how, and when”: A comprehensive investigation of the relation between syntactic skills and reading comprehension

open access: yes, 2023
Reading comprehension, or the understanding of written texts, is a vital skill for full engagement in school and society, and, as such, is among the most important skills children learn in elementary school.
MacKay, Elizabeth
core  

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