Results 61 to 70 of about 1,725,169 (334)

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Interpretable weld quality prediction in ultrasonic metal welding using change point detection

open access: yesDiscover Mechanical Engineering
Ultrasonic metal welding is a widely used process for joining metals to create electrical connections using high-frequency mechanical vibrations. Despite its industrial relevance, achieving consistent joint quality remains challenging and requires a ...
Oliver Stockemer   +5 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

A New Thesis concerning Synchronised Parallel Computing - Simplified Parallel ASM Thesis

open access: yes, 2015
A behavioural theory consists of machine-independent postulates characterizing a particular class of algorithms or systems, an abstract machine model that provably satisfies these postulates, and a rigorous proof that any algorithm or system stipulated ...
Ferrarotti, Flavio   +3 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Sensing-Assisted Secure Communications over Correlated Rayleigh Fading Channels

open access: yesEntropy
We consider a secure integrated sensing and communication (ISAC) scenario, where a signal is transmitted through a state-dependent wiretap channel with one legitimate receiver with which the transmitter communicates and one honest-but-curious target that
Martin Mittelbach   +4 more
doaj   +1 more source

FEA model study of spectral signature patterns of PM demagnetisation faults in synchronous PM machines

open access: yesThe Journal of Engineering, 2019
This work reports a finite element analysis (FEA) model study of the stator current spectra of a commercial permanent magnet (PM) AC machine operating with rotor PM demagnetisation faults.
Juan I. Melecio   +2 more
doaj   +1 more source

Spiral Vector Theory of Synchronous Machine

open access: yesIEEJ Transactions on Industry Applications, 1995
The spiral vector method was applied to the analysis of the transient phenomena of synchronous machines. Analytical results obtained were compared with test results on sudden three-phase short circuit currents. Good agreement was obtained for the first time.
openaire   +3 more sources

Machine learning in acoustics: Theory and applications [PDF]

open access: yesThe Journal of the Acoustical Society of America, 2019
Acoustic data provide scientific and engineering insights in fields ranging from biology and communications to ocean and Earth science. We survey the recent advances and transformative potential of machine learning (ML), including deep learning, in the field of acoustics.
Bianco, Michael J.   +6 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy