Results 231 to 240 of about 696,315 (263)

Programmable Compliance in Small‐Diameter Vascular Grafts by Design of Melt‐Electrowritten Scaffold Architectures for In Situ Tissue Engineering

open access: yesAdvanced Healthcare Materials, EarlyView.
Small‐diameter vascular grafts with compliance tunable by design are fabricated via melt electrowriting. By controlling the winding angle of intertwined helical fibers, grafts with compliances matching those of human vessels, from veins to arteries, are realized. This holds the potential of avoiding a compliance mismatch, which has been identified as a
Kilian Maria Arthur Mueller   +8 more
wiley   +1 more source

Norbornene Homopolymerization Limits Cell Spreading in Thiol–Ene Photoclick Hydrogels

open access: yesAdvanced Healthcare Materials, EarlyView.
Thiol–norbornene click reactions are often used in the development of cell‐permissive 3D hydrogels. However, ene–ene crosslinks in other thiol–ene systems are known to limit permissivity. This study demonstrates the negative effects of norbornene homopolymerization on 3D cell spreading and circumvents the issue by modulating polymer degree of ...
James L. Gentry, Steven R. Caliari
wiley   +1 more source

Silencing Myostatin Using In Vivo Self‐Assembled siRNA Protects Against Cancer‐ and Dexamethasone‐Induced Muscle Atrophy

open access: yesAdvanced Healthcare Materials, EarlyView.
This study reports an in vivo self‐assembled siRNA strategy that enables the liver to generate small extracellular vesicles (sEVs) tagged with a muscle‐targeting peptide (MSP) and naturally loaded with myostatin (MSTN)‐siRNA. These MSP‐tagged sEVs are systemically delivered to skeletal muscle, efficiently silence MSTN, promote muscle hypertrophy, and ...
Xin Yin   +14 more
wiley   +1 more source

Recombinant Proteins: A Molecular Tool to Understand Marine Adhesion and to Advance Biomaterials

open access: yesAdvanced Healthcare Materials, EarlyView.
The production of recombinant proteins represents a fundamental step in the characterisation of marine invertebrate adhesives and in the development of bio‐inspired glues. The association of these proteins with other components such as ions, proteins, polysaccharides, or polymers enables the fabrication of biomaterials for various healthcare ...
Alessandra Whaite   +4 more
wiley   +1 more source

Natural‐Based Nanocomposite Ink Engineering for Seamless Multi‐Material Integration in Extrusion‐Based 3D Printing

open access: yesAdvanced Healthcare Materials, EarlyView.
This innovative ink engineering strategy enables the integration of bioactive nanocomposites into complex, multi‐material constructs. By combining primary chemical coupling and post‐printing photocuring, the study achieves tunable printability, seamless material integration, and robust mechanical performance.
João R. Maia   +7 more
wiley   +1 more source

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