Results 181 to 190 of about 3,785,147 (434)
Description of a Machine for Shaping the Models Used in Experiments on Forms of Ships [PDF]
, 1873 William Froude
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Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Application of the stability lobes theory to milling of thin workpieces, experimental approach [PDF]
, 2003 The optimisation of cutting conditions in High Speed Machining (HSM) requires the use of a vibratory approach in order to avoid a fast deterioration of the tool and of the spindle, as well as a loss of quality of the surface rough- ness.
Arnaud, Lionel, Dessein, Gilles
core
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
A comparative study on trajectory tracking control methods for automated vehicles
Scientific ReportsTrajectory tracking control, as the core component of the autopilot system, is essential for achieving high-performance autopilot functionality. Therefore, to design a trajectory-tracking controller that is stable, reliable, accurate, fast, and robust ...
Dequan Zeng +8 more
doaj +1 more source
Machining technique prevents undercutting in tensile specimens [PDF]
, 1968 Machining technique prevents undercutting at the test section in tensile specimens when machining the four corners of the reduced section. Made with a gradual taper in the test section, the width of the center of the tensile specimen is less than the ...
Moscater, R. E., Royster, D. M.
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FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source