Results 41 to 50 of about 3,502,209 (342)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
The Mechanism of Layer Stacked Clamping (LSC) for Polishing Ultra-Thin Sapphire Wafer
Micromachines, 2020 Double-sides polishing technology has the advantages of high flatness and parallelism, and high polishing efficiency. It is the preferred polishing method for the preparation of ultra-thin sapphire wafer.
Zhixiang Chen +5 more
doaj +1 more source
FEBS Letters, EarlyView.The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet +4 more
wiley +1 more source
Experimental study on lapping ceramic balls with variable-radius groove plate
Advances in Mechanical Engineering, 2021 The method of lapping precision ball with variable-radius groove is developed in recent years. An experimental study on lapping ceramic balls with variable-radius groove was carried out.
Fenfen Zhou +5 more
doaj +1 more source
Newtonian Mechanics Based Transient Stability PART II: Individual Machine [PDF]
arXiv, 2021 The paper analyzes the mechanisms of the individual-machine and also its advantages in TSA. Based on the critical-machine monitoring of the original system trajectory, it is clarified that the individual-machine strictly follows the machine paradigms. These strict followings of the paradigms bring the two advantages of the individual-machine method in ...
arxiv
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Application of an Ultrashort-pulsed Laser for Generation of Super-hydrophobic Surfaces
Current Directions in Biomedical Engineering, 2021 Hydrophobic surfaces have gained a vast attention in different fields of biomedical applications over the last few years. Laser treatment has been shown as a promising technology for the generation of functional, inter alia, superhydrophobic surfaces. In
Zahedi Ali +2 more
doaj +1 more source
Newtonian Mechanics Based Transient Stability PART IV: Equivalent Machine [PDF]
arXiv, 2021 This paper analyzes the mechanisms of the equivalent machine and also its advantages in TSA. Based on the two group separations, an equivalent machine is modeled through the equivalence of the motions of all machines inside each group. This "motion equivalence" fully ensures the modeling of the two-machine system and the corresponding Newtonian energy ...
arxiv
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022 Abstract Purpose A set of treatment planning strategies were designed and retrospectively implemented for locally advanced, non‐small cell lung cancer (NSCLC) patients in order to minimize cardiac dose without compromising target coverage goals. Methods Retrospective analysis was performed for 20 NSCLC patients prescribed to 60–66 Gy that received a ...
Joshua P. Kim +5 more
wiley +1 more source