Results 61 to 70 of about 119,208 (317)

Optimization experiment on eccentric lapping of cylindrical rollers

open access: yesNanotechnology and Precision Engineering, 2018
Cylindrical rollers are important elements of bearings, and their machining accuracy and consistency affect the bearing quality. Using a GCr15 cylindrical roller of Ф11 × 12 as the processing object in this study, the effects of loading pressure ...
Jia Su   +3 more
doaj   +1 more source

On 'Machine Consciousness'

open access: yesJournal of Artificial Intelligence and Consciousness, 2023
Consciousness in higher animals, by virtue of its 100 millisecond time constant, is a necessarily greatly simplified and stripped-down version of more complex multiple tunable workspace cognition/regulation dyads like wound healing, immune function, gene expression, institutional function and the like.
openaire   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Aqueous lubrication and surface microstructures of engineering polymer materials (PEEK and PI) when sliding against Si3N4

open access: yesFriction, 2017
Polyether-ether-ketone (PEEK) and polyimide (PI) are two kinds of engineering polymer materials widely used as roller bearing cages and rings under extreme environment because of their noise reduction and corrosion resistance properties.
Anying Wang   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The Mechanism of Layer Stacked Clamping (LSC) for Polishing Ultra-Thin Sapphire Wafer

open access: yesMicromachines, 2020
Double-sides polishing technology has the advantages of high flatness and parallelism, and high polishing efficiency. It is the preferred polishing method for the preparation of ultra-thin sapphire wafer.
Zhixiang Chen   +5 more
doaj   +1 more source

Gradient droplet distribution promotes spontaneous formation of frost-free zone

open access: yesCommunications Materials, 2022
Preventing the condensation of water is key for anti-icing applications. Here, a macro-ridged surface is found to prevent frost formation either side of each ridge, attributed to a change in water vapor distribution preventing ice bridge formation.
Chenguang Lu   +7 more
doaj   +1 more source

The effects of machining process variables and tooling characterisation on the surface generation: modelling, simulation and application promise

open access: yes, 2005
The paper presents a novel approach for modelling and simulation of the surface generation in the machining process. The approach, by integrating dynamic cutting force model, regenerative vibration model, machining system response model and tool profile ...
Cheng, K, Luo, X, Ward, R
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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