Results 81 to 90 of about 119,208 (317)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Sensors, 2022 Great progress has been made in the field of ultrasonic processing in recent years, and piezoelectric ceramic transducers have been widely used as drive sources. In this paper, a sandwich piezoelectric ceramic transducer is designed, and the vibration of
Yuren Lu +4 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Barkhausen Noise Emission in Milled Surfaces
Communications, 2015 This paper deals with the non-destructive evaluation of surface made of roll bearing steel 100Cr6 after milling cycles via Barkhausen noise technique.
Miroslav Neslusan +3 more
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Application of an Ultrashort-pulsed Laser for Generation of Super-hydrophobic Surfaces
Current Directions in Biomedical Engineering, 2021 Hydrophobic surfaces have gained a vast attention in different fields of biomedical applications over the last few years. Laser treatment has been shown as a promising technology for the generation of functional, inter alia, superhydrophobic surfaces. In
Zahedi Ali +2 more
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
TechnologiesOne of the limitations of additive manufacturing technology is the high surface roughness of finished products caused by the layered structure of the deposition and the effect of adhesion of unfused powder particles.
Sergey N. Grigoriev +9 more
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International Journal of Advanced Robotic Systems, 2019 Composite workpieces, especially the complex-curved surfaces composite workpieces, have been increasingly used in different industries. Non-destructive testing of these parts has become an urgent problem to be addressed.
Canzhi Guo +4 more
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Conduction-Based Thermally Assisted Micromilling Process for Cutting Difficult-to-Machine Materials
Journal of Manufacturing and Materials Processing, 2020 The increasing demand for complex and wear-resistant forming tools made of difficult-to-machine materials requires efficient manufacturing processes. In terms of high-strength materials; highly suitable processes such as micromilling are limited in their
Timo Platt +2 more
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