Results 61 to 70 of about 3,639,668 (395)
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
Study on ultrasonic regulation of the welding performance and defects of 7A52 aluminum alloy plate
AIP Advances, 2022 The welding performance and defects of thick aluminum alloy plates with medium and high strength are always a hot research topic. In this study, ultrasonic technology was used to regulate the properties and defects of welded joints of a 7A52 aluminum ...
Peng Yin +4 more
doaj +1 more source
Metals, 2023 In this study, TiB + La2O3/Ti-6Al-4V composites were successfully prepared by in situ reaction using selective laser melting technology. The effect of LaB6 content on the fabrication quality, microstructure evolution and mechanical properties of the ...
Dongdong He +5 more
doaj +1 more source
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
FEBS Letters, EarlyView.Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source
Sensors, 2022 Great progress has been made in the field of ultrasonic processing in recent years, and piezoelectric ceramic transducers have been widely used as drive sources. In this paper, a sandwich piezoelectric ceramic transducer is designed, and the vibration of
Yuren Lu +4 more
doaj +1 more source
Topological model for machining of parts with complex shapes [PDF]
, 2012 Complex shapes are widely used to design products in several industries such as aeronautics, automotive and domestic appliances. Several variations of their curvatures and orientations generate difficulties during their manufacturing or the machining of ...
Bernard, Alain +2 more
core +2 more sources
FEBS Letters, EarlyView.Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley +1 more source
Optimization of roughing operations in cnc machining for rapid manufacturing processes [PDF]
, 2013 This paper presents a method for optimizing roughing operations in CNC machining particularly for parts production through a subtractive rapid manufacturing process. The roughing operation in machining is primarily used to remove the bulk of the material
Case, Keith +2 more
core
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source