Results 81 to 90 of about 1,214,762 (295)

Cold machining of high density tungsten and other materials [PDF]

open access: yes, 1969
Cold machining process, which uses a sub-zero refrigerated cutting fluid, is used for machining refractory or reactive metals and alloys.
Ziegelmeier, P.
core   +1 more source

SPH method applied to high speed cutting modelling [PDF]

open access: yes, 2007
The purpose of this study is to introduce a new approach of high speed cutting numerical modelling. A Lagrangian smoothed particle hydrodynamics (SPH)- based model is arried out using the Ls-Dyna software.
Chieragatti, Rémy   +4 more
core   +3 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Significant Influence on Residual Bending Strength by Cracks Generation During Grinding of Ceramics

open access: yesChinese Journal of Mechanical Engineering
Any product must undergo precise manufacturing before use. The damage incurred during the manufacturing process can significantly impact the residual strength of the product post-manufacturing.
Jinshuo Zhang   +5 more
doaj   +1 more source

Cutting Performance of Different Coated Micro End Mills in Machining of Ti-6Al-4V

open access: yesMicromachines, 2018
Tool wear is a significant issue for the application of micro end mills. This can be significantly improved by coating materials on tool surfaces. This paper investigates the effects of different coating materials on tool wear in the micro milling of Ti ...
Zhiqiang Liang   +5 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

A machine learning forecasting model for COVID-19 pandemic in India [PDF]

open access: bronze, 2020
R. Sujath   +2 more
openalex   +1 more source

Identification of machining defects by Small Displacement Torsor and form parameterization method [PDF]

open access: yes, 2010
In the context of product quality, the methods that can be used to estimate machining defects and predict causes of these defects are one of the important factors of a manufacturing process.
Bui, Minh-Hien   +5 more
core   +2 more sources

On the Machinability of an Al-63%SiC Metal Matrix Composite [PDF]

open access: yes, 2020
This paper presents a preliminary study of aluminium matrix composite materials during machining, with a special focus on their behavior under conventional processes.
Batista Ponce, Moisés   +4 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

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