Results 51 to 60 of about 2,330,665 (285)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Effects of Machining Errors on Optical Performance of Optical Aspheric Components in Ultra-Precision Diamond Turning

open access: yesMicromachines, 2020
Optical aspheric components are inevitably affected by various disturbances during their precision machining, which reduces the actual machining accuracy and affects the optical performance of components.
Yingchun Li   +4 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

The Accuracy of Forming Rectangular Tenons by End-Pressing without Guiding Tooling

open access: yesЛесной журнал
The article presents an analysis of experimental data on the manufacturing accuracy of tenon joint elements in pine workpieces produced by end pressing without using locating-clamping tooling.
Yaroslav D. Vedernikov   +4 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

A study of electrodischarge machining–pulse electrochemical machining combined machining for holes with high surface quality on superalloy

open access: yesAdvances in Mechanical Engineering, 2015
Noncircular holes on the surface of turbine rotor blades are usually machined by electrodischarge machining. A recast layer containing numerous micropores and microcracks is easily generated during the electrodischarge machining process due to the rapid ...
Ning Ma   +5 more
doaj   +1 more source

Limiting current density in electrochemical micromachining

open access: yesJournal of Electrochemical Science and Engineering, 2018
In this paper, a method of calculating the diffusion current density on the electric pole in the electrochemical micromachining is proposed. Changes of the diffusion current with system factors are investigated from which a method of increasing the ...
Chuanjun Zhao, Lizhong Xu
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Research on adaptive belt grinding aeroengine titanium alloy fan blades

open access: yesJin'gangshi yu moliao moju gongcheng, 2018
Most aeroengine blades are made of titanium alloys, which have good strength and mechanical properties, but poor machinability. The surface precision and surface quality of the blades after precision forging and precision milling need to be machined to ...
ZHANG Hongzhi   +5 more
doaj  

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Home - About - Disclaimer - Privacy