Results 101 to 110 of about 43,039 (317)

Numerical and Experimental Investigation for Stability Lobes Prediction in Thin Wall Machining [PDF]

, 2009
A Finite Element Analysis (FEA) and Fourier transform approach to obtain frequency response function (FRF) is presented in this paper. The aim in this paper is to eliminate the need for the classical impact experimental approach used in extracting ...
Sim, W.M., Adetoro, O.B., Vepa, R., Wen, PH, Vepa, R, Adetoro, OB, Sim, WM, Wen, P.H.   +7 more
core  

Experimental Research and Significance Analysis of Advanced Interpolation Methods for Optimizing System State Items and Processing Parameters

Machines
The Finite-Difference Method (FDM) plays a pivotal role in the field of stability prediction, particularly in the modeling and stability analysis of cutting process dynamics.
Chunlei Tian, Yan Cao, Tian Chen, Tianlong Yuan   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Modeling and Optimal Design of Machining-Induced Residual Stresses in Aluminium Alloys Using a Fast Hierarchical Multiobjective Optimization Algorithm [PDF]

, 2011
The residual stresses induced during shaping and machining play an important role in determining the integrity and durability of metal components. An important issue of producing safety critical components is to find the machining parameters that create ...
Yates, John R., Greene, Richard J., Boumaiza, Soufiene, Mahfouf, Mahdi, Zhang, Qian, de Leon, Luis, Richard J. Greene, Christophe Pinna, John R. Yates, Pinna, Christophe, Soufiene Boumaiza, George Panoutsos, Qian Zhang, Panoutsos, George, Mahdi Mahfouf, Luis de Leon   +15 more
core   +1 more source

The Influence of Laser Cutting Parameters on the Heat-Affected Zone in Fast-Growing Malaysian Wood Species

Journal of Manufacturing and Materials Processing
Wood is a naturally occurring renewable resource widely used in various industries, including in construction, packaging, furniture, and paneling. In Malaysia, 80% of furniture products are made from wood, making it a crucial material in this sector ...
Mohd Sharizal Sobri, Sharizal Ahmad Sobri, Mohd Natashah Norizan, Andi Hermawan, Mohd Hazim Mohamad Amini, Mazlan Mohamed, Wan Omar Ali Saifuddin Wan Ismail, Al Amin Mohamed Sultan   +7 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Balancing Productivity and Sustainability in EDM: A Comprehensive Analysis of Energy Consumption and Electrode Degradation

Machines
Die-sinking Electrical Discharge Machining (EDM) is a manufacturing process for fabricating complex geometries in challenging applications. However, its energy-intensive nature and complex parameter interactions pose challenges in balancing productivity,
Sunil Kumar Maurya, Gianni Campatelli, Massimo Veracini, Massimo Arcioni, Dario Clori   +4 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Multi-Objective Process Parameter Optimization for Abrasive Air Jet Machining Using Artificial Bee Colony Algorithm

Machines
Abrasive air jet machining is a burgeoning non-traditional machining technology particularly suitable for machining brittle non-metallic materials and metals with high hardness.
Xiaozhi Fan, Quanlai Li, Weipeng Zhang, Haonan Yin   +3 more
doaj   +1 more source