Results 51 to 60 of about 97,519 (271)

Replicode: A Constructivist Programming Paradigm and Language [PDF]

open access: yes, 2013
Replicode is a language designed to encode short parallel programs and executable models, and is centered on the notions of extensive pattern-matching and dynamic code production.
Nivel, Eric, Thórisson, Kristinn R.
core  

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

DNA Array Analysis in a Microsoft® Windows® Environment

open access: yesBioTechniques, 2002
Microsoft® Windows®-based computers have evolved to the point that they provide sufficient computational and visualization power for robust analysis of DNA array data.
T. Conway   +5 more
doaj   +1 more source

Spontaneous Subtle Expression Detection and Recognition based on Facial Strain

open access: yes, 2016
Optical strain is an extension of optical flow that is capable of quantifying subtle changes on faces and representing the minute facial motion intensities at the pixel level.
Liong, Sze-Teng   +6 more
core   +1 more source

Real‐world trends in prenatal antirheumatic drug utilization in Ontario, Canada: A cross‐sectional time‐series analysis

open access: yesArthritis Care &Research, Accepted Article.
Objectives This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah   +6 more
wiley   +1 more source

Integrated-Skills and Segregated-skills approaches in the teaching of Speaking for EFL Learners

open access: yesRevue des Sciences Humaines, 2022
The current study aims at exploring whether teachers follow the integrated-skills or the segregated-skills approach in the process of teaching the speaking skill in Oral Expression module. It also attempts to examine the learning/teaching process of the
Ouided ARAB , Riad Belouahem
doaj  

Research on the Identification of a Winter Olympic Multi-Intent Chinese Problem Based on Multi-Model Fusion

open access: yesApplied Sciences, 2023
Aiming at addressing the inability of traditional web technologies to effectively respond to Winter-Olympics-related user questions containing multiple intentions, this paper explores a multi-model fusion-based multi-intention recognition model BCNBLMATT
Pingshan Liu, Qi Liang, Zhangjing Cai
doaj   +1 more source

Facial Micro- and Macro-Expression Spotting and Generation Methods [PDF]

open access: yes, 2023
Facial micro-expression (ME) recognition requires face movement interval as input, but computer methods in spotting ME are still underperformed. This is due to lacking large-scale long video dataset and ME generation methods are in their infancy.
Yap, Chuin Hong
core  

Additive Manufacturing of Continuous Fibre Reinforced Composites: Process, Characterisation, Modelling, and Sustainability

open access: yesAdvanced Engineering Materials, EarlyView.
Additive manufacturing provides precise control over the placement of continuous fibres within polymer matrices, enabling customised mechanical performance in composite components. This article explores processing strategies, mechanical testing, and modelling approaches for additive manufactured continuous fibre‐reinforced composites.
Cherian Thomas, Amir Hosein Sakhaei
wiley   +1 more source

Home - About - Disclaimer - Privacy