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Penicurvularins A and B, macrolides from an ascomycete fungus <i>Alternaria</i> sp. [PDF]
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Organic Letters, 2023
Two previous unreported epipolythiodioxopiperazines of the emestrin family, namely, noremestrin A (1) and secoemestrin E (2), were successfully isolated from the fungal source Emericella sp. 1454. Employing comprehensive spectroscopic techniques, such as
Yuchuan Chen +12 more
semanticscholar +1 more source
Two previous unreported epipolythiodioxopiperazines of the emestrin family, namely, noremestrin A (1) and secoemestrin E (2), were successfully isolated from the fungal source Emericella sp. 1454. Employing comprehensive spectroscopic techniques, such as
Yuchuan Chen +12 more
semanticscholar +1 more source
Journal of the American Veterinary Medical Association, 2021
OBJECTIVE To determine whether ABCB11930_1931del TC predisposed cats to macrocyclic-lactone toxicosis and the frequency of the ABCB11930_1931del TC gene mutation in banked feline DNA samples.
K. Mealey +2 more
semanticscholar +1 more source
OBJECTIVE To determine whether ABCB11930_1931del TC predisposed cats to macrocyclic-lactone toxicosis and the frequency of the ABCB11930_1931del TC gene mutation in banked feline DNA samples.
K. Mealey +2 more
semanticscholar +1 more source
Resistance to Macrocyclic Lactones
Current Pharmaceutical Biotechnology, 2012Resistance to the macrocyclic lactones (MLs) has been confirmed or suspected in many target organisms and is a serious problem in some. For some species, such as parasitic nematodes of small ruminants, ML resistance has become severe enough to threaten effective worm control worm control.
Adrian J, Wolstenholme, Ray M, Kaplan
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Macrocyclic lactone endectocides
2012The macrocyclic lactone endectocides such as ivermectin, abamectin, selamectin and moxidectin have revolutionized the treatment of parasitic diseases in animals, being active against internal and external parasites. Ivermectin was introduced into veterinary medicine in the 1980s and since that time a number of related compounds have been introduced. In
Sharon M. Gwaltney-Brant +2 more
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Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment, 2020
The study aimed to evaluate the effects of heat on macrocyclic lactone residues in cows’ milk. Ivermectin, abamectin, doramectin, eprinomectin and moxidectin were added to raw milk in three concentrations.
B. Avci, A. Filazi
semanticscholar +1 more source
The study aimed to evaluate the effects of heat on macrocyclic lactone residues in cows’ milk. Ivermectin, abamectin, doramectin, eprinomectin and moxidectin were added to raw milk in three concentrations.
B. Avci, A. Filazi
semanticscholar +1 more source
Macrocyclic lactone resistance in cyathostomins
Veterinary Record, 2008SIR, — The beginning of resistance of cyatho stomins to the macrocyclic lac-tones has been suggested by the less than complete reduction in egg counts after treatment with ivermectin in Germany ([von Samson-Himmelstjerna and others 2007][1]), the occurrence of eggs in faeces 28 days ...
Dudeney, A, Campbell, C, Coles, GC
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Macrocyclic Lactones and Dirofilaria immitis Microfilariae
Topics in Companion Animal Medicine, 2011Although there has been extensive veterinary focus on both the effectiveness of macrocyclic lactones for heartworm prevention in dogs and their adulticidal effects, little attention has been directed to their effects on heartworm microfilariae. With routine use of macrocyclic lactones, in some cases knowingly, in dogs with existing heartworm infections,
Dwight D, Bowman, Claire, Mannella
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Synergism of macrocyclic lactones against Haemonchus contortus
Parasitology Research, 2023A possible synergistic effect of macrocyclic lactones' (MLs) combination has been previously described against resistant gastrointestinal nematodes of cattle. In addition to synergism, drug-drug interactions between MLs can also result in additive or antagonistic effect, considering the different MLs pharmacokinetics, pharmacodynamics, and interactions
Matheus Takemi Muchon Nakatani +8 more
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Macrocyclic lactone resistance in Dirofilaria immitis
Veterinary Parasitology, 2011Microfilariae were isolated from a Katrina rescue dog that remained microfilariaemic despite successful adulticidal treatments and repeated treatment with high doses of macrocyclic lactones (MLs). The microfilariae were genotyped at two P-glycoprotein single nucleotide polymorphic sites which had been found to correlate with reduced sensitivity to MLs.
Catherine, Bourguinat +5 more
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