Results 71 to 80 of about 113,437 (249)

Gastrointestinal nematodes of Ovis aries in Eastern Cape, South Africa and an evaluation of current anthelmintic procedures [PDF]

, 2015
Humans have known about helminth infections since ancient times. Today half of the human population is plagued by a nematode infection. Nematodes are responsible for billions of dollars in global crop damage annually and have had devastating effects on ...
Rowell, Melyssa
core   +1 more source

Synthesis and biological evaluation of new salicylate macrolactones from anacardic acids [PDF]

, 2005
No âmbito de uma linha de pesquisa que visa a obtenção de novas substâncias bioativas, a partir de lipídeos fenólicos não-isoprenóides de Anacardium occidentale, descrevemos a síntese e avaliação citotóxica de novas macrolactonas salicílicas, preparadas ...
Cavalcanti, Bruno Côelho, Costa-Lotufo, Leticia Veras, Logrado, Lucio Paulo Lima, Moraes, Manoel Odorico de, Pessoa, Cláudia do Ó, Romeiro, Luiz Antonio Soares, Santos, Maria Lucilia dos, Silveira, Dâmaris   +7 more
core   +2 more sources

Parasite management practices used by owners of Australian Pony Club horses and the factors influencing their decision‐making processes

Australian Veterinary Journal, EarlyView.
There is a lack of information on horse parasite management practices currently used by individual horse owners in Australia. A voluntary, anonymous online survey was developed for and distributed by Pony Club Australia to its members seeking information on horse population; housing; paddock, manure and parasite management; and owner attitudes.
W Nixon, P Buckley, R Butler
wiley   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

Stereoselective Access to Z and E Macrocycles by Ruthenium-Catalyzed Z-Selective Ring-Closing Metathesis and Ethenolysis [PDF]

, 2013
The first report of Z-selective macrocyclizations using a ruthenium-based metathesis catalyst is described. The selectivity for Z macrocycles is consistently high for a diverse set of substrates with a variety of functional groups and ring sizes.
Grubbs, Robert H., Herbert, Myles B., Keitz, Benjamin K., Marx, Vanessa M.   +3 more
core   +1 more source

Sustainable control of cyathostomin infections in practice

Equine Veterinary Education, EarlyView.
Summary Cyathostomins are the most prevalent helminths in horses and are found in nearly all grazing groups. These parasites have been shown to exhibit widespread anthelmintic resistance and can cause clinical disease, so they are a growing concern.
J. B. Matthews, T. S. Mair
wiley   +1 more source

Differential ABC transporter gene expression in adult Dirofilaria immitis males and females following in vitro treatment with ivermectin, doxycycline or a combination of both

Parasites & Vectors, 2019
Background Combination doxycycline/macrocyclic lactone (ML) protocols have been shown to provide a more rapid adulticidal and microfilaricidal effect than either MLs or doxycycline alone, although female worms were reported to have a higher tolerance to ...
Chiara Lucchetti, Marco Genchi, Luigi Venco, Alessandro Menozzi, Paolo Serventi, Simone Bertini, Chiara Bazzocchi, Laura Helen Kramer, Alice Vismarra   +8 more
doaj   +1 more source

Comparative efficacy of Moxidectin and Ivermectin in cattle naturally infected with old world screw worm larvae [PDF]

Iraqi Journal of Veterinary Sciences, 2005
Moxidectin is a second generation semi-synthetic Macrocyclic Lactone of the Milbemycins family, which have a broad spectrum of activity against external and internal parasite including Oestrus ovis and hypodermatosis.
E A Hassan, A Y Al-Karogholli, A S Hassan, M O Al-Ani   +3 more
doaj   +1 more source

Chemistry and Biology of Streptogramin A Antibiotics [PDF]

, 2007
The streptogramin A antibiotics have proven to be highly active against Gram positive bacteria, particularly methicillin-resistant Staphylococcus aureus. Members of this group of compounds are characterized by a 23-membered macrocycles containing polyene,
Ahmed, Fahim, Donaldson, William
core   +1 more source

Fluorine in fragrances : exploring the difluoromethylene (CF2) group as a conformational constraint in macrocyclic musk lactones [PDF]

, 2016
The authors thank EPSRC for a grant. CNvH also thanks the Fluorine Division of the American Chemical Society for a Moissan Summer Undergraduate Fellowship.
Buehl, Michael, Cordes, David Bradford, Cormanich, Rodrigo, Corr, Michael James, O'Hagan, David, Slawin, Alexandra Martha Zoya, von Hahmann, Cortney   +6 more
core   +1 more source