Results 11 to 20 of about 163,193 (205)

Macrocytic anemia in Lesch–Nyhan disease and its variants [PDF]

Genetics in Medicine, 2019
Purpose: Lesch-Nyhan disease is an inherited metabolic disorder characterized by overproduction of uric acid and neurobehavioral abnormalities. The purpose of this study was to describe macrocytic erythrocytes as another common aspect of the phenotype ...
Gul Yalcin Çakmakli, Christopher C Porter, Hasan Fatih Çakmakli   +2 more
exaly   +4 more sources

Macrocytic anemia is associated with the severity of liver impairment in patients with hepatitis B virus-related decompensated cirrhosis: a retrospective cross-sectional study

BMC Gastroenterology, 2018
Background Macrocytic anemia is common in liver disease. However, its role in hepatitis B virus (HBV)-related decompensated cirrhosis remains unknown.
Jian Yang, Bin Yan, Lihong Yang, Huimin Li, Yajuan Fan, Feng Zhu, Jie Zheng, Xiancang Ma   +7 more
doaj   +2 more sources

Hematinic deficiencies and anemia statuses in oral mucosal disease patients with folic acid deficiency [PDF]

Journal of the Formosan Medical Association, 2015
Folic acid deficiency (FAD) may result in macrocytic anemia. This study assessed the hematinic deficiencies and anemia statuses in oral mucosal disease patients with FAD (defined as folic acid ≤ 6 ng/mL). Methods: The blood hemoglobin (Hb), iron, vitamin
Julia Yu-Fong Chang, Yi-Ping Wang, Yang-Che Wu, Shih-Jung Cheng, Hsin-Ming Chen, Andy Sun   +5 more
doaj   +3 more sources

Splenomegaly in a Patient with a History of Pernicious Anemia; the Potential Therapeutic Effects of B12 Therapy

Case Reports in Hematology, 2022
Splenomegaly is manifested by a variety of etiologies, one of which is macrocytic anemia. Macrocytic anemia has multiple causes in itself that include; folate (Vitamin B9) and Cobalamin (vitamin B12) deficiencies.
Alexis Lordi, Nida Ansari, Michael Maroules, Anusha Manjegowda   +3 more
doaj   +2 more sources

Spontaneous resolution of macrocytic anemia: old disease revisited

Journal of Blood Medicine, 2012
Shinsaku Imashuku, Naoko Kudo, Shigehiro KanedaDivision of Hematology, Takasago-seibu Hospital, Takasago, JapanAbstract: We report here on a 60-year-old male with alcohol-related macrocytic anemia.
Imashuku S, Kudo N, Kaneda S
exaly   +2 more sources

Middle Eastern Adolescent With Macrocytic Anemia [PDF]

Global Pediatric Health, 2017
Sneha Butala BS, Brian Berman MD
doaj   +2 more sources

Serum biomarker analysis may guide management of anemia in patients with chronic liver disease [PDF]

Frontiers in Medicine
BackgroundChronic liver disease (CLD) is a significant global health threat and has emerged as one of the leading causes of mortality worldwide.
Yihui Rong, Wenpeng Fu, Yanyu Jiang, Xudong Gao, Jie Han   +4 more
doaj   +2 more sources

Severe Macrocytic Anemia Associated With a Novel <i>ALAS2</i> Mutation: A Case Report and Literature Review. [PDF]

Clin Case Rep
ABSTRACT X‐linked sideroblastic anemia (XLSA), caused by pathogenic variants in ALAS2, typically presents as microcytic anemia in males. However, heterozygous females occasionally exhibit an atypical macrocytic phenotype, often leading to diagnostic ambiguity and confusion with nutritional anemias or myelodysplastic syndromes.
Cai H, Shen K, Wang J, Gu J, Zhang M, Xiao M.   +5 more
europepmc   +2 more sources

Macrocytic Anemia and Mitochondriopathy Resulting from a Defect in Sideroflexin 4 [PDF]

, 2013
We used exome sequencing to identify mutations in sideroflexin 4 (SFXN4) in two children with mitochondrial disease (the more severe case also presented with macrocytic anemia).
Hildick-Smith, Gordon J, Akman, H. Orhan, Branco, Diana S, Mootha, V.K., Lieber, D.S., Thon, Jonathan N., Shah, Dhvanit I., Freedman, Matthew L, Kremer, Laura S., Yien, Yvette Y, Huston, Nicholas C, Thon, J.N., Merkenschlager, Andreas, Branco, D.S., Thon, Jonathan N, Mootha, Vamsi K, Hildick-Smith, G.J., Lieber, Daniel S., Haack, T.B., Mootha, Vamsi K., Cooney, J.D., Huston, Nicholas C., Strom, T.M., Hildick-Smith, Gordon J., Prokisch, H., Cooney, Jeffrey D, Kremer, L.S., Calvo, S.E., Calvo, Sarah E, Koehler, Carla M., Haack, Tobias B., Calvo, Sarah E., Prokisch, Holger, Paw, B.H., DiMauro, Salvatore, Koehler, C.M., Miyata, Non, Huston, N.C., Freedman, M.L., Lieber, Daniel S, Akman, H.O., Beblo, S., Italiano, Joseph E, Italiano, Joseph E., Beblo, Skadi, Meitinger, Thomas, DiMauro, S., Shah, D.I., Garone, C., Shah, Dhvanit I, Strom, Tim M., Paw, Barry H., Freisinger, P., Akman, H Orhan, Branco, Diana S., Yien, Yvette Y., Strom, Tim M, Donati, M.A., Meitinger, T., Freisinger, Peter, Yien, Y.Y., Kremer, Laura S, Garone, Caterina, Koehler, Carla M, Miyata, N., Italiano, J.E., Haack, Tobias B, Cooney, Jeffrey D., Merkenschlager, A., Freedman, Matthew L., Donati, M. Alice, Paw, Barry H, Donati, M Alice   +72 more
core   +3 more sources

Neonatal Diamond-Blackfan anemia with persistent neutropenia caused by an <i>RPS15A</i> variant. [PDF]

Pediatr Investig
Pediatric Investigation, EarlyView.
Zheng H, Wang K, Wang J, Fang J, Zhou D, Qiu K.   +5 more
europepmc   +2 more sources