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American family physician, 1996
In approximately 2 to 4 percent of patients, laboratory evidence of macrocytosis is found. Macrocytic anemias are classified as those resulting from disorders of DNA synthesis of erythrocyte precursors in bone marrow (megaloblastic anemias) or those caused primarily by alcoholism, liver disease and hypothyroidism (nonmegaloblastic anemias).
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In approximately 2 to 4 percent of patients, laboratory evidence of macrocytosis is found. Macrocytic anemias are classified as those resulting from disorders of DNA synthesis of erythrocyte precursors in bone marrow (megaloblastic anemias) or those caused primarily by alcoholism, liver disease and hypothyroidism (nonmegaloblastic anemias).
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La Revue du praticien, 1989
Macrocytic and/or megaloblastic anaemias of infants and children are more often due to a defective bone marrow production than to haemolysis. They are mostly related to folate and/or cobalamin deficiency or to a disturbance in the metabolism of one of these vitamins (enzyme deficiencies or defect of synthesis of their active forms).
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Macrocytic and/or megaloblastic anaemias of infants and children are more often due to a defective bone marrow production than to haemolysis. They are mostly related to folate and/or cobalamin deficiency or to a disturbance in the metabolism of one of these vitamins (enzyme deficiencies or defect of synthesis of their active forms).
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PERNICIOUS ANEMIA AND RELATED MACROCYTIC ANEMIAS
Archives of Internal Medicine, 1945To the Editor: I should like to present the following concept of pernicious anemia and related macrocytic anemias for the consideration of your readers. Just as pellagra is no longer considered a "disease" if the skin, gastrointestinal tract or nervous system lut is classified rather as a vitamin deficiency disorder, manifested by a disturbance in the
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MACROCYTIC ANEMIA OF PREGNANCY
Journal of the American Medical Association, 1944To the Editor:— The rare macrocytic anemia of pregnancy is a serious and incompletely understood disease. Some writers have considered it a form of pernicious anemia, but most observers have been impressed particularly by its resemblance to the hemolytic anemias.
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Thrombotic Microangiopathy-Like Hemolysis in Vitamin B12 Deficiency-Related Macrocytic Anemia.
Clinical Laboratory, 2018M. Yamanishi +4 more
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Hemolysis contributes to anemia during long-duration space flight
Nature Medicine, 2022Guy Trudel +2 more
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