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Prevalence of potential underlying aetiology of macrocytic anaemia in Dutch general practice [PDF]

open access: yesBMC Family Practice, 2016
Background: Macrocytic anaemia (MCV \xe2\x89\xa5 100 fL) is a relatively common finding in general practice. However, literature on the prevalence of the different causes in this population is limited.
Rob Castel   +2 more
exaly   +4 more sources

The Macrocytic Anemias

Laboratory Medicine, 1990
Megaloblastic anemias result from processes that disrupt DNA synthesis. The condition is usually acquired, with medications, cobalamin, or folate deficiency being common precipitating factors. Many patients with cobalamin or folate deficiency will present with hematologic abnormalities, such as anemia or pancytopenia, along with macroovalocytes and ...
John A. Glaspy, Steven M. Scates
openaire   +2 more sources

Evaluation of Macrocytic Anemias

Seminars in Hematology, 2015
Macrocytic anemia, defined as a mean cell volume (MCV) ≥100 fL in adults, has a narrow differential diagnosis that requires evaluation of the peripheral blood smear as well as additional laboratory testing taken in conjunction with clinical information that includes patient history and physical examination findings.
Ralph Green, Denis M. Dwyre
openaire   +3 more sources

Macrocytic anemias

Postgraduate Medicine, 1977
Macrocytic anemias are not uncommon in clinical practice, and precise etiologic diagnosis is mandatory for proper management. Measurement of serum levels of vitamin B12 and folic acid may obviate the need for extensive diagnostic studies.
openaire   +2 more sources

Clinching the diagnosis: macrocytic anemia

Pathology, 1988
Macrocytosis is a common laboratory finding. Whether this change requires further attention is dictated by clinical circumstances and concomitant cytopenias or aberrant erythrocyte and leukocyte morphology. The utility of these changes for dictating further investigation and the appropriate "modus operandi" in diagnostic strategies for the adult and ...
Lynda Campbell, Martin B. Van Der Weyden
openaire   +3 more sources

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