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Macrocytic anemias

Current Opinion in Hematology
Purpose of review Over the last century, the diseases associated with macrocytic anemia have been changing with more patients currently having hematological diseases including malignancies and myelodysplastic syndrome. The intracellular mechanisms underlying the development of anemia with macrocytosis can help in understanding ...
Mark J, Koury, Daniel J, Hausrath
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TREATMENT OF MACROCYTIC ANEMIAS

Archives of Internal Medicine, 1955
ANEMIAS characterized by large erythrocytes (MCV > 95) are usually caused by lack of one of the erythrocyte maturation factors, vitamin B12or folinic acid. Under these circumstances the young erythrocytes in the bone marrow are megaloblastic and maturation of myeloid elements and megakaryocytes is bizarre.
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Normocytic and macrocytic anemias

Postgraduate Medicine, 1991
Differential diagnosis of normocytic and macrocytic anemias is guided by the patient history, physical examination results, reticulocyte count, and specific red blood cell abnormalities identified on the peripheral smear. In some cases this information is sufficient for diagnosis.
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Macrocytic anemia of pregnancy and anemia of the newborn

American Journal of Obstetrics and Gynecology, 1939
Abstract The relationship of macrocytic anemia of pregnancy with a severe anemia of the newborn is herein reported, with a discussion of the etiologic factors involved. We believe that the anemia of both the mother and the infant is due to a dietary deficiency.
Joseph A. Ritter, Walter J. Crocker
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MACROCYTIC ANEMIA OF PREGNANCY

Journal of the American Medical Association, 1944
To the Editor:— The rare macrocytic anemia of pregnancy is a serious and incompletely understood disease. Some writers have considered it a form of pernicious anemia, but most observers have been impressed particularly by its resemblance to the hemolytic anemias.
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Macrocytic hyperchromic anemia in children

Acta Paediatrica, 1939
Summary.The authors describe a case of macrocytic hyperchromic anemia in celiac disease in a girl of 8 1/2 years who, five years earlier, presented a clinical picture typical of celiac disease combined with anemia.A likely cause of the disease picture in this case is a paratyphoid infection incurred in early infancy (the first half of the second month).
Bertil Hamne, J. Henning Magnusson
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Macrocytic hyperchromic anemia of pregnancy

American Journal of Obstetrics and Gynecology, 1942
Abstract 1. 1. A case of a severe grade of macrocytic hyperchromic anemia induced by pregnancy is presented. 2. 2. It was recognized and successfully treated with hlood transfusion and parenteral liver therapy. 3. 3. A living male child was delivered spontaneously. 4. 4. A blood count of the child revealed no abnormalities.
Max Antis, Mark Daniel
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Investigation of macrocytic anemia

Postgraduate Medicine, 1979
This article on microcytic anemia is the first of several on laboratory investigation of anemia. Microcytic anemia, characterized by a mean corpuscular volume of less than 80 cu mu, is usually due to iron deficiency or chronic disease but may signify thalassemia minor. Exact identification of the cause is important, since inappropriate iron therapy may
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PERNICIOUS ANEMIA AND RELATED MACROCYTIC ANEMIAS

Archives of Internal Medicine, 1945
To the Editor: I should like to present the following concept of pernicious anemia and related macrocytic anemias for the consideration of your readers. Just as pellagra is no longer considered a "disease" if the skin, gastrointestinal tract or nervous system lut is classified rather as a vitamin deficiency disorder, manifested by a disturbance in the
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DIVERTICULOSIS OF THE JEJUNUM WITH MACROCYTIC ANEMIA AND STEATORRHEA

Annals of Internal Medicine, 1961
Excerpt Jejunal diverticulosis complicated by macrocytic anemia and steatorrhea has been rarely reported, and the syndrome has remained relatively unknown to the medical profession.
Abraham A. Polachek   +2 more
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