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Macrocytosis secondary to hydroxyurea therapy
Veterinary Clinical Pathology, 2017AbstractA 10‐year‐old, male neutered Shetland Sheepdog was presented to the University of Florida for evaluation of a well‐granulated mast cell tumor. Hydroxyurea therapy was instituted and serial CBCs showed persistent mild anemia and macrocytosis without a corresponding increase in polychromasia.
Francisco O, Conrado +3 more
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Macrocytosis Associated with Divalproex Treatment
Journal of Child and Adolescent Psychopharmacology, 2005Divalproex (DVP) is increasingly prescribed to children and adolescents in psychiatric practices. Among the hematologic adverse effects of DVP, decreased platelet count is well described in the medical literature. However, to date, few studies describe the occurrence of macrocytosis as an adverse effect of divalproex.
Ruth, Tsivkin +2 more
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The Clinical Significance of Macrocytosis
Acta Medica Scandinavica, 1981ABSTRACT. The cause of macrocytosis (mean corpuscular volume (MCV) ≥105 fl) was investigated over a period of 16 months in the 70 known cases of ± 4000 patients seen by the Department of Internal Medicine. By means of simple laboratory investigations the cause of elevated MCV was found in more than 90% of the cases.
F C, Breedveld +2 more
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Macrocytosis and Cyclophosphamide
JAMA: The Journal of the American Medical Association, 1974To the Editor.— The recent article by Drs. Klippel and Decker (229:180, 1974), "Relative Macrocytosis in Cyclophosphamide and Azathioprine Therapy," emphasized an observation that we have been making for some time. These drugs do indeed produce megaloblastosis of the bone marrow, and low-grade macrocytosis of the circulating erythrocytes.
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Macrocytosis of the Erythrocytes
JAMA, 1964In a three-month study using precise modern laboratory techniques, macrocytosis of the erythrocytes often occurred in the absence of anemia and of the classical macrocytic diseases. Disorders in which it occurred most frequently were (1) cirrhosis, (2) malignant disease, (3) acute blood loss, and (4) megaloblastic disorders.
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American family physician, 2009
Macrocytosis, generally defined as a mean corpuscular volume greater than 100 fL, is frequently encountered when a complete blood count is performed. The most common etiologies are alcoholism, vitamin B12 and folate deficiencies, and medications. History and physical examination, vitamin B12 level, reticulocyte count, and a peripheral smear are helpful
Joyce, Kaferle, Cheryl E, Strzoda
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Macrocytosis, generally defined as a mean corpuscular volume greater than 100 fL, is frequently encountered when a complete blood count is performed. The most common etiologies are alcoholism, vitamin B12 and folate deficiencies, and medications. History and physical examination, vitamin B12 level, reticulocyte count, and a peripheral smear are helpful
Joyce, Kaferle, Cheryl E, Strzoda
openaire +1 more source