Results 51 to 60 of about 4,121 (154)

Hypomorphic ATP11c is a novel regulator of decreased efficacy of transfused red blood cells in humans and mice

HemaSphere, Volume 10, Issue 1, January 2026.
Abstract Chronic red blood cell (RBC) transfusion sustains patients with diverse hematologic disorders, but repeated transfusion leads to iron overload and alloimmunization. Reducing transfusion burden requires identifying donor units that circulate more effectively after storage, yet determinants of this variability remain incompletely defined.
James C. Zimring, Ariel M. Hay, Monika Dzieciatkowska, Daniel Stephenson, Zachary B. Haiman, Steven Kleinman, Philip J. Norris, Michael P. Busch, Nareg Roubinian, Elisa Fermo, Paola Bianchi, Gregory R. Keele, Grier P. Page, Angelo D'Alessandro   +13 more
wiley   +1 more source

Erythropoiesis in health and disease: Distinguishing defective and ineffective erythropoiesis

HemaSphere, Volume 10, Issue 1, January 2026.
Abstract Erythropoiesis is a finely regulated process ensuring continuous red blood cell production to maintain oxygen delivery. Disruptions in this process give rise to defective erythropoiesis, characterized by impaired lineage commitment and progenitor development, and ineffective erythropoiesis (IE), marked by expansion of erythroid progenitors ...
Sara El Hoss, Maria A. Lizarralde‐Iragorri, Thiago Trovati Maciel, Olivier Hermine   +3 more
wiley   +1 more source

Hematinic deficiencies and anemia statuses in anti-gastric parietal cell antibody-positive or all autoantibodies-negative erosive oral lichen planus patients

Journal of the Formosan Medical Association, 2018
Approximately 27% of erosive oral lichen planus (EOLP) patients have serum anti-gastric parietal cell antibody (GPCA) positivity. This study assessed whether serum GPCA or EOLP itself was a significant factor that caused hematinic deficiencies and anemia
Julia Yu-Fong Chang, Yi-Ping Wang, Yu-Hsueh Wu, Yu-Xuan Su, Yu-Kang Tu, Andy Sun   +5 more
doaj   +1 more source

A novel PIEZO1 mutation in a patient with dehydrated hereditary stomatocytosis: a case report and a brief review of literature

Italian Journal of Pediatrics, 2020
Background Dehydrated hereditary stomatocytosis (DHS) or hereditary xerocytosis is a rare, autosomal dominant hemolytic anemia characterized by macrocytosis, presence of stomatocytes and dehydration of red blood cells (RBCs). The dehydration is caused by
Daniele Zama, Giulia Giulietti, Edoardo Muratore, Immacolata Andolfo, Roberta Russo, Achille Iolascon, Andrea Pession   +6 more
doaj   +1 more source

What Is Your Diagnosis? Multiple Subcutaneous Lumps in a Horse

Veterinary Clinical Pathology, EarlyView.
Federica Meistro, Maria Virginia Ralletti, Riccardo Rinnovati, Alessandro Spadari, Maria Morini   +4 more
wiley   +1 more source

Exploring low haemoglobin density as a no‐added‐cost screening marker to assess iron deficiency

Vox Sanguinis, Volume 121, Issue 1, Page 35-42, January 2026.
Abstract Background and Objectives Iron deficiency (ID), with or without anaemia, affects over 1 billion people globally. Early detection is essential, but current diagnostic tools may be costly, logistically complex and not widely accessible. This study evaluates low haemoglobin density percentage (LHD%), derived from mean corpuscular haemoglobin ...
Jesse Qiao, Sherif Rezk, Gagan Mathur
wiley   +1 more source

Skin Hyperpigmentation as Initial Manifestation of Vitamin B12 Deficiency: A Case of Delayed Diagnosis With Late‐Onset Subacute Combined Degeneration of the Cord

Case Reports in Medicine, Volume 2026, Issue 1, 2026.
Vitamin B12 deficiency may present with a myriad of symptoms. Rarely, skin hyperpigmentation may be the sole initial manifestation of this micronutrient deficiency, which can easily be overlooked, leading to delayed diagnosis. This case report describes a 32‐year‐old Ghanaian male who presented with a 4‐year history of progressive darkening of the ...
Prosper Adjei, Kingsley Owusu Manu, Paa Kwesi Asante Addison, Emmanuel Ntow, Rafael Scaf De Molon   +4 more
wiley   +1 more source

Hematinic deficiencies and anemia in gastric parietal cell antibody-positive and -negative oral submucous fibrosis patients

Journal of Dental Sciences, 2018
Background/purpose: Previous studies showed that approximately 13–15% of male oral submucous fibrosis (OSF) patients are serum gastric parietal cell antibody (GPCA)-positive.
Chun-Pin Chiang, Julia Yu-Fong Chang, Yu-Hsueh Wu, Andy Sun, Yi-Ping Wang, Hsin-Ming Chen   +5 more
doaj   +1 more source

Cerebral Edema Secondary to Heavy Metal Toxicity From Siddha Medicine: A Case Report and Case‐Based Review

Case Reports in Neurological Medicine, Volume 2026, Issue 1, 2026.
Background Traditional Indian medicine has been used to treat a variety of illnesses for centuries. However, there are existing concerns surrounding its heavy metal content. Amongst the different systems of traditional Indian medicine, Ayurvedic medicine has been most frequently implicated in heavy metal toxicity, while Siddha medicine has only very ...
Zhibin Tan, Bernard Ji Guang Chua, Mingwei Ng, Sophia Reyes, Stella Setiawan, You Jiang Tan, Boon Kiat Kenneth Tan, Ponampalam R., Dominic B. Fee   +8 more
wiley   +1 more source

Magnetic resonance imaging findings within the posterior and lateral columns of the spinal cord extended from the medulla oblongata to the thoracic spine in a woman with subacute combined degeneration without hematologic disorders: a case report and review of the literature

Journal of Medical Case Reports, 2011
Introduction Subacute combined degeneration of the spinal cord is a rare cause of demyelination of the dorsal and lateral columns of the spinal cord and is a neurological complication of vitamin B12 deficiency.
Tizniti Siham, Belahsen Faouzy, Khibri Hajar, Maaroufi Mustapha, Rabhi Samira, Berrady Rhizlane, Bono Wafaa   +6 more
doaj   +1 more source