Results 111 to 120 of about 32,992 (301)

Preferential accumulation of selectively-preserved macromolecular substances in the humus peat deposit as seen by analytical pyrolysis and spectroscopic techniques

open access: yes, 2003
A series of structural features of the three main humic fractions (humic acid, fulvic acid and humin) from different depths of a peat bog deposit in Mazago´n (Huelva, Southern Spain) were isolated and analysed by flash pyrolysis–gas chromatography–mass ...
González-Pérez, José Antonio   +5 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Phytomass Valorization by Deep Eutectic Solvents—Achievements, Perspectives, and Limitations

open access: yes, 2020
In recent years, a plethora of extraction processes have been performed by a novel class of green solvents known as deep eutectic solvents (DESs), possessing several environmental, operational, and economic advantages proven by experience when compared ...
Jozef Šima, Michal Jablonský
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Adsorption of Glyphosate by humic substances

open access: yes, 1996
Four humic substances were extracted from a peat (HA1) and a volcanic soil (HA2), an oxidized coal (HA3), and a lignite (HA4). The four humic materials presented distinct differences in their chemical and physical−chemical characteristics as assessed by ...
CELANO, Giuseppe, A. PICCOLO, P. CONTE
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Micelle-like conformation of humic substances as revealed by size exclusion chromatography

open access: yes, 1996
To gain further insight into the macromolecular behaviour of humic substances we treated a humic material with simple organic compounds and followed the change in molecular size distribution Monocarboxylic, dicarboxylic, and tricarboxylic acids shifted ...
PICCOLO A   +2 more
core   +1 more source

Control effect of kaolin in lignite on biological methane metabolism process

open access: yesMeitan kexue jishu
Kaolinite is a common mineral in coal, and its influence on the metabolic process of coal biological methane is less concerned. In this study, lignite and kaolin after demineralization were selected to explore the control effect of kaolin on coal bio-gas
Hongyu GUO   +6 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

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