Results 51 to 60 of about 68,115 (310)

The application of label-free imaging technologies in transdermal research for deeper mechanism revealing

open access: yesAsian Journal of Pharmaceutical Sciences, 2021
The penetration behavior of topical substances in the skin not only relates to the transdermal delivery efficiency but also involves the safety and therapeutic effect of topical products, such as sunscreen and hair growth products. Researchers have tried
Danping Zhang   +4 more
doaj  

Hydroboration-Oxidation of (±)-(1α,3α,3aβ,6aβ) -1,2,3,3a,4,6a-Hexahydro-1,3-pentalenedimethanol and Its O-Protected Derivatives: Synthesis of New Compounds Useful for Obtaining (iso)Carbacyclin Analogues and X-ray Analysis of the Products

open access: yesMolecules, 2017
Hydroboration-oxidation of 2α,4α-dimethanol-1β,5β-bicyclo[3.3.0]oct-6-en dibenzoate (1) gave alcohols 2 (symmetric) and 3 (unsymmetric) in ~60% yield, together with the monobenzoate diol 4a (37%), resulting from the reduction of the closer benzoate by ...
Constantin I. Tănase   +4 more
doaj   +1 more source

Identification of compositional and structural changes in the nucleus pulposus of patients with cervical disc herniation by Raman spectroscopy

open access: yesFrontiers in Endocrinology, 2022
PurposeCervical disc herniation (CDH) is one of the most common spinal diseases in modern society; intervertebral disc degeneration (IVDD) has long been considered as its primary cause.
Zhiqi Wang   +9 more
doaj   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Humic Substances: From Supramolecular Aggregation to Fractal Conformation—Is There Time for a New Paradigm?

open access: yesApplied Sciences, 2023
Natural organic matter, including humic substances (HS), comprises complex secondary structures with no defined covalent chemical bonds and stabilized by inter- and intra-molecular interactions, such as hydrogen bonding, Van der Waal’s forces, and pi-pi ...
Ruggero Angelico   +5 more
doaj   +1 more source

A new kinetic model for predicting polyamide 6-6 hydrolysis and its mechanical embrittlement [PDF]

open access: yes, 2012
PA 6-6 hydrolysis at 60, 70, 80 and 90 °C in distilled water has been studied by Fourier transform infrared spectroscopy, viscometry in molten state, differential scanning calorimetry and uniaxial tensile testing.
COLIN, Xavier   +2 more
core   +5 more sources

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

THE ASSESSMENT OF ANALYTICAL DOUBLE-SHOT PYROLYSIS WITH GAS CHROMATOGRAPH-MASS SPECTROMETRY APPLICATION OPPORTUNITY FOR THE HUMIC MATTER INVESTIGATION IN SITU

open access: yesБюллетень Почвенного института им. В.В. Докучаева, 2018
Double-shot pyrolysis with gas chromatography and mass detection (Double-shot GC MS) was conducted for a sample of typical chernozem and humic acids separated from it. The humic acids preparations were pyrolyzed at 500, 600 and 700°C.
V. A. Kholodov   +3 more
doaj   +1 more source

Production, reproduction, and reversion of protoplast-like structures in the osmotic strain of Neurospora crassa [PDF]

open access: yes, 1958
Protoplasts devoid of cell walls have been produced in Bacillus megaterium and certain other Gram-positive species of bacteria.(1) Structures resembling protoplasts but not completely devoid of cell walls have also been produced in Escherichia coli and ...
Emerson, Mary R., Emerson, Sterling
core  

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

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