Results 71 to 80 of about 72,853 (343)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Role of LncRNAs in regulating cancer amino acid metabolism

Cancer Cell International, 2021
The metabolic change of tumor cells is an extremely complicated process that involves the intersection and integration of various signal pathways. Compared with normal tissues, cancer cells show distinguished metabolic characteristics called metabolic ...
Yuhong Guo, Bin Lv, Renfeng Liu, Zhengzai Dai, Feifei Zhang, Yiping Liang, Bo Yu, Duo Zeng, Xiao-Bin Lv, Zhiping Zhang   +9 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Analysis of Carbon Tetrachloride-Extractable Species from Daxing Bituminous Coal

Applied Sciences, 2020
Soxhlet extraction (SE), ultrasonic-assisted extraction (UAE), and microwave-assisted extraction (MAE) were carried out on Daxing coal with carbon tetrachloride.
Caixia Jv, Fenggang Li, Peng Yan, Mengmeng Fan, Linlin Jia, Hong Zhang, Xianyong Wei, Zhimin Zong   +7 more
doaj   +1 more source

Mitigation of GHGs Emission From Soils by a Catalyzed In-Situ Photo-Oxidative Polymerization of Soil Organic Matter [PDF]

, 2010
Agricultural lands under food and bio-energy crops, managed grass and permanent crops including agro-forestry, occupy about 40-50% of the Earth's land surface^1^. In 2005, agriculture accounted for an estimated emission of 5.1 to 6.1 GtCO2-eq/yr (10-
Alessandro Piccolo, Riccardo Spaccini
core   +1 more source

Investigation of the influence of polyelectrolytes hydrodynamic properties on the hydrate formation process [PDF]

, 2018
One of the most perspective non-traditional sources of hydrocarbon raw materials and energy is gas hydrates (GH), which stimulates their large-scale study in many laboratories and scientific centers around the world.
Bondarenko, Volodymyr, Klymenko, Vasyl, Sai, Kateryna, Svietkina, Olena, Бондаренко, В. И., Бондаренко, В. І., Бондаренко, Владимир Ильич, Бондаренко, Володимир Ілліч, Сай, Е. С., Сай, Екатерина, Сай, К. С., Сай, Катерина   +11 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Recent trends and developments in pyrolysis-gas chromatography: review [PDF]

, 2008
Pyrolysis-gas chromatography (Py-GC) has become well established as a simple, quick and reliable analytical technique for a range of applications including the analysis of polymeric materials.
Arias, Armitage, Aslan, Asperger, Asperger, Asperger, Asperger, Bertini, Beyer, Blackledge, Blokker, Bonaduce, Bruck, Buckley, Buco, Campbell, Casas-Catalán, Causin, Challinor, Challinor, Challinor, Chang, Chiavari, Choi, Choi, Colombini, De Koeijer, De la Cruz-Canizares, Dignac, Doménech-Carbó, Doménech-Carbó, Dunn, Dzierzega-Lecznar, Dzierzega-Lecznar, Egan, Erickson, Evans, Evans, Fabbri, Fabbri, Fanter, Fifield, Flodin, Garcette-Lepecq, Gleixner, González-Vila, Goodacre, Greenwood, Greenwood, Greenwood, Greenwood, Guo, Gupta, Göbbels, Gözet, Halket, Halket, Heffenden, Herrera, Horrocks, Ikeya, Ishikawa, Islas, Jakab, Jamin, Jansson, Jarde, Jia, Jin, Jose Gonzalez-Rodriguez, Karina L. Sobeih, Kechang, Kochanowski, Kumooka, Lattimer, Lazaro, Learner, Levy, Li, Ling, Liu, Mao, Marinari, Marinari, Mark Baron, Marques, Maynard, Meruva, Metz, Moldoveanu, Mowry, Munson, Mäkinen, Nierop, Odermatt, Odermatt, Oguz, Ohshima, Osete-Cortina, Osete-Cortina, Osete-Cortina, Park, Parsi, Parsi, Parsi, Parsi, Partouche, Pasch, Peacock, Pel, Pel, Perng, Perng, Petsch, Poerschmann, Poirier, Prasad, Prati, Raghavan, Raulin, Ristau, Ristolainen, Rodriguez, Ross, Räisänen, Sakayanagi, Scalarone, Schmidt, Schwarzinger, Sephton, Sessions, Snyder, Stauffer, Stout, Stout, Stout, Suelves, Sugden, Sun, Sundarrajan, Suuronen, Takayasu, Takayasu, Tanczos, Thomsen, Tsai, Tsuge, Tsuge, Tzamtzis, Urakami, Uyar, Uyar, Vanderborgh, Volkman, Wampler, Wampler, Wampler, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wang, White, Wilkes, Wilkes, Yamamoto, Yang, Yaylayan, Yinon, Zhang, Zhou, Zhu, Zimmerman, Zlotnick, Çoban-Yildiz, Łakomy   +179 more
core   +1 more source