Results 161 to 170 of about 934,203 (313)
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
In Situ Incorporation of Macromolecules in Zr-MOF Membranes for Separation of Organic Azeotropic Mixtures. [PDF]
Li L +7 more
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
A simple method for freeze-drying of macromolecules and macromolecular complexes
Kathryn E. Loesser, C Franzini-Armstrong
openalex +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
ATP Can Act as a Stabilizer on Neutral Macromolecules. [PDF]
Ayvaz C +4 more
europepmc +1 more source
Design, synthesis, and investigation of a visible light-driven photo-switching macromolecule
Juan Pang +5 more
openalex +2 more sources

